Neural Circuits that Contribute to Procurement of Water
It is more than 18 years since Jim Stevenson and I observed a strong and persistent drinking response in rats receiving electrical stimulation of the lateral hypothalamus1. We had, according to the Zeitgeist of the mid-1960’s, activated the hypothalamic “thirst center”. It turned out, after some reflection, that there was a good deal of vagueness about this interpretation. However, the assumption was that by stimulating the so-called hypothalamic “thirst center” we activated a brain site concerned with integrating thirst signals and with generating “command signals” for the procurement and ingestion of water2.
KeywordsLocomotor Activity Nucleus Accumbens Zona Incerta Ingestive Behavior Straight Alley
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