Neural Circuits that Contribute to Procurement of Water

  • Gordon J. Mogenson
  • Blanche Box
Part of the NATO ASI Series book series (NSSA, volume 105)


It is more than 18 years since Jim Stevenson and I observed a strong and persistent drinking response in rats receiving electrical stimulation of the lateral hypothalamus1. We had, according to the Zeitgeist of the mid-1960’s, activated the hypothalamic “thirst center”. It turned out, after some reflection, that there was a good deal of vagueness about this interpretation. However, the assumption was that by stimulating the so-called hypothalamic “thirst center” we activated a brain site concerned with integrating thirst signals and with generating “command signals” for the procurement and ingestion of water2.


Locomotor Activity Nucleus Accumbens Zona Incerta Ingestive Behavior Straight Alley 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Gordon J. Mogenson
    • 1
  • Blanche Box
    • 1
  1. 1.Department of PhysiologyUniversity of Western OntarioLondonCanada

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