The Nature and Localization of Central Receptor Systems

  • John B. Simpson
Part of the NATO ASI Series book series (NSSA, volume 105)


The purpose of this paper is to consider the nature and the localization of central receptor systems involved in the control of fluid intake. Inherent in a discussion of these topics is a consideration of how such information describing receptor systems is obtained. Two commonly used techniques which are well suited to such analyses are the experimental brain lesion and its variants, and the intracranial chemical injection. Although other techniques can and often are applied to the questions of localization and nature of central systems, it is truly only in experiments that employ the measurement of specific ingestive behavior that such central mechanisms may be directly understood. Other techniques, which may be described as ancillary, do indeed provide relevant information regarding the organization for central behavioral mechanisms; however, it is only by the use of behavior as the dependent measure that a definitive understanding of those brain systems relevant to behavior can be achieved.


Cerebral Ventricle Vasopressin Secretion Sensitive Site Circumventricular Organ Intracranial Injection 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • John B. Simpson
    • 1
  1. 1.Department of Psychology, NI-25University of WashingtonSeattleUSA

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