Satiety and the Effects of Water Intake on Vasopressin Secretion
Two stimuli have been identified in the control of drinking which follows a period of water deprivation. When animals are deprived of water, but not food, extracellular fluid volume decreases and extracellular fluid osmolality rises. In dehydrated dogs, removal of the volume deficit reduces subsequent drinking by 27%, whereas removal of the central osmotic stimulus decreases water intake by 72%.1 Although the proportions may vary, other species show volume and osmotic components in dehydration induced thirst2,3.
KeywordsWater Deprivation Plasma Osmolality Vasopressin Secretion Gastric Fistula Volume Deficit
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