Satiety and the Effects of Water Intake on Vasopressin Secretion

  • David J. Ramsay
  • Terry N. Thrasher
Part of the NATO ASI Series book series (NSSA, volume 105)


Two stimuli have been identified in the control of drinking which follows a period of water deprivation. When animals are deprived of water, but not food, extracellular fluid volume decreases and extracellular fluid osmolality rises. In dehydrated dogs, removal of the volume deficit reduces subsequent drinking by 27%, whereas removal of the central osmotic stimulus decreases water intake by 72%.1 Although the proportions may vary, other species show volume and osmotic components in dehydration induced thirst2,3.


Water Deprivation Plasma Osmolality Vasopressin Secretion Gastric Fistula Volume Deficit 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • David J. Ramsay
    • 1
  • Terry N. Thrasher
    • 1
  1. 1.Physiology DepartmentUniversity of CaliforniaSan Francisco San FranciscoUSA

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