Histamine Plays a Role in Drinking Elicited by Eating in the Rat

  • F. Scott Kraly
Part of the NATO ASI Series book series (NSSA, volume 105)


Eating elicits the vagally-mediated1 release of histamine from endocrinelike non-mast cells2 in the gastric mucosa of the rat.3 Exogenous histamine elicits drinking in the rat.4,5 To examine whether eating elicits drinking through a histaminergic mechanism, a pharmacological probe was developed to block drinking elicited by systemic histamine in male Sprague-Dawley rats.


Sham Feeding Methyl Nitrate Atropine Methyl Nitrate Gastric Vagal Exogenous Histamine 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • F. Scott Kraly
    • 1
  1. 1.Department of PsychologyColgate UniversityHamiltonUSA

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