Abstract
The volume and composition of the extracellular fluid is controlled within very narrow limits in terrestrial mammals. This process depends upon the ability of the animal to vary urinary volume and concentration over a wide range and on the ability to regulate water intake homeostatically.1 Additionally, it is becoming clear that sodium excretion and possibly sodium intake may also be regulated in order to maintain a constancy of plasma osmolality.2 For example, if a dog is deprived of water for 24 hours while allowed access to food, its plasma osmolality increases by approximately 10 mosmol/Kg. This is accomplished by renal conservation of water together with a marked natriuresis. Dogs will rapidly make up their water deficits when allowed access to water.3 The major emphasis in this review will be the mechanisms which regulate water intake.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
D.J. Ramsay, T.W. Thrasher and L.C. Keil, Stimulation and inhibition of drinking and vasopressin secretion in dogs, in Antidiuretic Hormone, S. Yoshida, L. Share and K. Yagi eds., University Park Press, Baltimore, 97, 1979.
T.N. Thrasher, C.E. Wade, L.C. Keil and D.J. Ramsay, Sodium balance and aldosterone during dehydration and rehydration in the dog, Am. J. Physiol 247 (Regulatory, Integrative Comp. Physiol 16) R76, 1984.
D.J. Ramsay, B.J. Rolls and R.J. Wood, Thirst following water deprivation in dogs. Am. J. Physiol 232 (Regulatory, Integrative, Comp Physiol 1) R93, 1977.
A. Gilman, The relation between blood osmotic pressure, fluid distribution and voluntary water intake, Am. J. Physiol 120, 323, 1937.
J.H. Holmes and M.I. Gregersen, Role of sodium and chloride in thirst, Am. J. Physiol 162, 1950.
J.H. Holmes and M.I. Gregersen, Observations on drinking induced by hypertonic solutions, Am. J. Physiol. 162, 1950.
T.N. Thrasher, Osmoreceptor mediation of thirst and vasopressin secretion in the dog, Federation Proc. 41, 2528, 1982.
E.B. Verney, The antidiuretic hormone and the factors which govern its release, Proc. Royal Soc. London Series B. 135, 1947.
C.E. Wade, P. Bie, L.C. Keil and D.J. Ramsay, Effect of hypertonic intracarotid infusions on plasma vasopressin concentration, Am. J. Physiol 243 (Endocrinol Metab 6) E522, 1982.
A.V. Wolf, Osmometric analysis of thirst in man and dog, Am. J. Physiol 161, 75, 1950.
B. Andersson, The effect of injections of hypertonic NaClsolutions into different parts of the hypothalamus of goats, Acta. Physiol. Scand 18, 1953.
S. Kozlowski and K. Drzewieski, The role of osmoreception in portal circulation in control of water intake in dogs. Acta. Physiol. Pol. 24, 1973.
P. Bie, Osmoreceptors, vasopressin and control of renal water excretion, Physiol Rev. 60, 1980.
J.W. Peck, and D. Novin, Evidence that osmoreceptors mediating drinking in rabbits are in the lateral preoptic area, J. Comp. Physiol. Psychol. 74, 1971.
E.M. Blass and A.N. Epstein, A lateral preoptic osmosensitive zone for thirst in the rat, J. Comp. Physiol. Psychol, 76, 1971.
R.J. Wood, B.J. Rolls and D.J. Ramsay, Drinking following intracarotid infusions of hypertonic solutions in dogs, Am. J. Physiol 232, (Regulatory, Integrative Comp Physiol 1) R88, 1977.
B. Andersson, Regulation of water intake, Physiol. Rev. 58, 1978.
T.N. Thrasher, C.J. Brown, L.C. Keil and D.J. Ramsay, Thirst and vasopressin release in the dog: an osmoreceptor or sodium receptor mechanism? Am. J. Physiol, 238 (Regulatory, Integrative Comp. Physiol 7) R333, 1980.
M.J. McKinley, D.A. Denton, and R.S. Weisinger, Sensors for antidiuresis and thirst — osmoreceptors or CSF sodium receptors? Brain, Res, 141, 1978.
J. Buggy and A.K. Johnson, Preoptic — hypothalamic periventricular lesions: thirst deficits and hypernatremia, Am. J. Physiol 233 (Regulatory, Integrative Comp. Physiol 2) R44, 1977.
J.T. Fitzsimons, Drinking by rats depleted of body fluid without increase in osmotic pressure, J. Physol (Lond), 159, 1961.
J.H. Holmes and A.V. Montgomery, Thirst as a sympton, Am. J. Med. Sci. 225, 1953.
S. Kozlowski and J. Sobocinska, Thirst in regulation of blood volume in dogs, In. Fourth Int. Cont. Regulation Food and Water Intake, Cambridge, 1971.
E.M. Stricker, Extracellular fluid volume and thirst, Am. J. Physiol 211, 1966.
J.T. Fitzsimons, The role of renal thirst factor in drinking induced by extracellular stimuli, J. Physiol (Lond) 201, 1969.
K. Yagi, H. Kannan and Y. Sawaki, Electrophynology of andiuretic hormone secreting neurons: afferent neural pathways from cardiovascular receptors, In Antidiuretic hormone, S. Yoshida, L. Share and K. Yagi eds., University Park Press, Baltimore, 81, 1979.
M.C. Lee, T.N. Thrasher and D.J. Ramsay, Is angiotensin essential in drinking induced by water deprivation and caval ligation? Am. J. Physiol 240 (Regulatory, Integrative Comp Physiol 9) R75, 1981.
J.T. Fitzsimons and R.W. Elfont, Angiotensin does contribute to drinking induced by caval ligation in the rat, Am. J. Physiol 243 (Regulatory, Integrative Comp Physiol 12) R558, 1982.
K.A. Houpt and A.N. Epstein, The complete dependence of betaadrenergic drinking on the renal dipsogen, Physiol Behav. 7, 1971.
D.J. Ramsay, Beta-Adrenergic thirst and its relations to the renin angiotensin system, Federation Proceed. 37, 1978.
R. Rettig, D. Ganten and A.K. Johnson, Isoproterenol-induced thirst: renal and extrarenal mechanisms, Am. J. Physiol 241, (Regulatory, Integrative Comp. Physiol 10) 152, 1981.
J.T. Fitzsimons and M.S. Moore-Gillon, Drinking and antidiuresis in response to reductions in venous return in the dog: neural and endocrine mechanisms, J. Physiol (Lond) 308, 1980.
T.N. Thrasher, L.C. Keil and D.J. Ramsay, Hemodynamic, hormonal and drinking responses to reducd venous return in the dog, Am. J. Physiol 243 (Regulatory, Integrative Comp. Physiol 12) R354, 1982.
C.E. Wade, L.C. Keil and D.J. Ramsay, Role of volume and osmolality in the control of plasma vasopressin in dehydrated dogs, Neuroendocrinology 37: 349, 1983.
R.J. Wood, E.T. Rolls and B.J. Rolls, Physiological mechanisms for thirst in the non-human primate, Am.J. Physiol 242 (Regulatory, Integrative Comp. Physiol 11) R423, 1982.
D.J. Ramsay, B.J. Rolls and R.J. Wood, Body fluid changes which influence drinking in the water deprived rat, J. Physiol (Lond) 266:453, 1977.
J.O. Davis, The physiology of congestive heart failure in Handbook of Physiology, Circulation, Washington, D.C., Am. Physiol. Soc., sect 2, vol III, 2071, 1965.
T.N. Thrasher, M. Moore-Gillon, C.E. Wade, L.C. Keil and D.J. Ramsay, Inappropriate drinking and secretion of vasopressin after caval constriction in dogs, Am. J. Physiol 244 (Regulatory, Integrative Comp Physiol 13) R850, 1983.
J.R. Blair-West, A.H. Brook, A. Gibson, M. Morris and P.T. Pullan, Renin, antidiuretic hormone and the kidney in water restriction and rehydration, J. Physiol (Lond) 294, 181, 1979.
E.G. Schneider, P.G. Davis and R.E. Taylor, Sodium modulation of aldosterone secretion by the isolated canine adrenal gland, Federation Proceedings 42, 1985.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer Science+Business Media New York
About this chapter
Cite this chapter
Ramsay, D.J., Thrasher, T.N. (1986). Hyperosmotic and Hypovolemic Thirst. In: de Caro, G., Epstein, A.N., Massi, M. (eds) The Physiology of Thirst and Sodium Appetite. NATO ASI Series, vol 105. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0366-5_13
Download citation
DOI: https://doi.org/10.1007/978-1-4757-0366-5_13
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-0368-9
Online ISBN: 978-1-4757-0366-5
eBook Packages: Springer Book Archive