Posterior Hypothalamic Polydipsia : Differential Effects to Several Dipsogenic Treatments

  • Alberto Morales
  • Amadeo Puerto
Part of the NATO ASI Series book series (NSSA, volume 105)


Water intake is a physiological process (primary or secondary) which can be triggered by several factors1,2,3 At the same time, the cerebral mechanisms controlling drinking have been related to several brain structures, i.e., the septal area4, circularis nucleus5, lateral hypothalamus6, subfornical organ7, etc.


Water Intake Septal Lesion Circumventricular Organ Increase Water Intake Sham Injection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    A.N. Epstein, D. Spector, A. Samman and C. Goldblum, Exaggerated prandial drinking in the rat without salivary glands. Nature. 201, 1342–1343 (1964).PubMedCrossRefGoogle Scholar
  2. 2.
    H. Valtin, Hereditary hypothalamic diabetes insipidus in the Brattleboro strain of rat. Am. J. of Pathology. 83(3), 633–636 (1976).Google Scholar
  3. 3.
    B. Andersson, Regulation of body fluids and salt appetite. Ann. Rev. Physiol., 39, 185–200 (1977).CrossRefGoogle Scholar
  4. 4.
    E.M. Blass and D.G. Hanson, Primary hyperdipsia in rat following septal lesions. J. Comp. Physiol. Psychol., 70(1), 87–93 (1970).PubMedCrossRefGoogle Scholar
  5. 5.
    G.I. Hatton, Nucleus Circularis: is it an osmoreceptor in the brain? Brain Res. Bull. 1(1), 123–131 (1976).PubMedCrossRefGoogle Scholar
  6. 6.
    J. Kucharczyk and G.J. Mogenson, Separate lateral hypothalamic pathways for extracellular and intracellular thirst. Am. J. Physiol. 228(1) 295–301 (1975).PubMedGoogle Scholar
  7. 7.
    J.B. Simpson, The circumventricular organs and the central actions of angiotensin. Neuroendocrinol. 32(4), 248–256 (1981).CrossRefGoogle Scholar
  8. 8.
    M. P. Tejedor del Real, M.P. Santacana-Altimiras and R. Alvarez-Pelaez, Alteración de la toma de agua después de la lesión de los Cuerpos Mamilares. Rev. Esp. Fisiol. 28, 95–102 (1972).PubMedGoogle Scholar
  9. 9.
    J.W. Hennessy, S.P. Grossman and M. Kanner, A study of the etiology of the hyperdipsia produced by coronal knife cuts in the posterior hypothalamus. Physiol. Behav. 18, 73–80 (1977).PubMedCrossRefGoogle Scholar
  10. 10.
    E.M. Blass, Separation of cellular from extracellular controls of drinking in rats by frontal brain damage. Science, 162, 1501–1503 (1968).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Alberto Morales
    • 1
  • Amadeo Puerto
    • 1
  1. 1.Laboratory of Psychobiology Department of PsychologyUniversity of GranadaCartujaSpain

Personalised recommendations