Retrospective Research on Clinical Laboratory Test Results Using a Hospital Information System. A preliminary Report

  • J. H. M. Zwetsloot-Schonk
  • M. Frolich
  • J. H. M. Souverijn


Test indices are often determined by comparing test results of healthy persons with test results of patients known with the disease. Test indices are, however, dependent on the characteristics of the population used for the calculation of the indices. The population for which the test will be ordered in routine medical practice usually differs from the characteristics of healthy persons and patients with advanced disease. It is necessary to recalculate the indices of a test once it is introduced in routine practice.

We investigated whether or not a general hospital information system can be used for this purpose. Prior considerations are given about the usefulness of a hospital information system.

From the characteristics of the hospital information system of the Leiden University Hospital we concluded that the sensitivity of clinical laboratory tests for the diagnosis of malignant tumors, can be reevaluated using data stored in the hospital information system. As an example we calculated the sensitivity of the prostatic acid phosphatase test for prostatic carcinoma.


Quinone Hyperparathyroidism Monophosphate Noma Thymol 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • J. H. M. Zwetsloot-Schonk
    • 1
  • M. Frolich
    • 2
  • J. H. M. Souverijn
    • 2
  1. 1.Central Development- And Support GroupLeidenThe Netherlands
  2. 2.Central Lab. for Clin. Chem.Leiden Univ. HospitalLeidenThe Netherlands

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