Immunology of Islet Cells

  • Edward R. Arquilla
  • David P. Stenger


Interest in the immunology of pancreatic islets has been sparked by the numerous clinical and experimental observations that an autoimmune mechanism is centrally involved in the pathogenesis of type I diabetes. Although much of this evidence is reviewed by Gepts and LeCompte (Chapter 16, this volume), it will be necessary to discuss possible immune mechanisms involved in experimental and clinical type I diabetes in this chapter.


Major Histocompatibility Complex Human Leukocyte Antigen Major Histocompatibility Complex Class Islet Cell Allograft Rejection 
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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • Edward R. Arquilla
    • 1
  • David P. Stenger
    • 1
  1. 1.Department of PathologyUniversity of California Irvine Medical CenterOrangeUSA

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