The Pathology of Type I (Juvenile) Diabetes

  • Willy Gepts
  • Philip M. LeCompte


Type I diabetes or insulin-dependent diabetes mellitus (IDDM), traditionally known as juvenile diabetes, is usually characterized clinically by an abrupt onset of symptoms, dependence on injected insulin, and proneness to ketosis. Classically, this type of diabetes occurs in young individuals, but it can develop at any age. Genetic, immunologic, epidemiologic, and clinical data1 suggest that type I diabetes is a heterogeneous group of diseases with different etiologies and a variable pathogenesis.


Islet Cell Diabetic Subject Pancreatic Polypeptide Islet Tissue Glucagon Cell 
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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • Willy Gepts
    • 1
  • Philip M. LeCompte
    • 2
  1. 1.Department of PathologyVrije Universiteit BrusselBrusselsBelgium
  2. 2.Gastroenterology DepartmentLemuel Shattuck Hospital and Tufts University School of MedicineBostonUSA

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