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Type II (Idiopathic) Diabetes (Non-Insulin-Dependent)

  • Bruno W. Volk
  • Klaus F. Wellmann

Abstract

The manifestations of diabetes mellitus, because of their complex and diversified nature, make it often difficult to categorize the various types of the disease. It is not a single disease, but rather a syndrome that may be produced by a number of factors. It may result from extrapancreatic lesions, such as hyperplasia or tumors of the anterior pituitary gland or the adrenal cortex or medulla, or hyperthyroidism. In some cases, diabetes may follow surgical removal of the pancreas, or its origin may be the destruction of the pancreatic islets resulting from pancreatic diseases such as hemochromatosis, pancreatitis, pancreatic lithiasis, and tumors of the pancreas.

Keywords

Diabetic Patient Pancreatic Islet Fatty Infiltration Experimental Diabetes Methyl Violet 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Marble, A.: In: Joslin’s Diabetes Mellitus. Edited by A. Marble, P. White, R. Bradley, and L. P. Krall. Lea & Febiger, Philadelphia, 1971, p. 1.Google Scholar
  2. 2.
    White, P.: Diabetes in Childhood and Adolescence. Lea & Febiger, Philadelphia, 1932, p. 60.Google Scholar
  3. 3.
    Boyd, J. D.: In: Practice of Pediatrics. Edited by J. Brenneman. Prior, Hagerstown, Md., 1946.Google Scholar
  4. 4.
    Danowski, T. S.: Diabetes Mellitus, With Emphasis on Children and Young Adults. Williams & Wilkins, Baltimore, 1957.Google Scholar
  5. 5.
    White, P.: Diabetes, 9:345, 1960.PubMedGoogle Scholar
  6. 6.
    White, P.: In: Diabetes. Edited by R. H. Williams. Hoeber, New York, 1960, p. 381.Google Scholar
  7. 7.
    Schwartzman, J., Crusius, M. E., and Beime, D. P.: Am. J. Dis. Child, 74:587, 1947.PubMedGoogle Scholar
  8. 8.
    Hoppe-Seyler, G.: Dtsch. Arch. Klin. Med, 81:119, 1904.Google Scholar
  9. 9.
    Cecil, R. L.: Exp. Med, 11:266, 1909.Google Scholar
  10. 10.
    Opie, E. L.: Diseases of the Pancreas. Lippincott, Philadelphia, 1910, p. 317.Google Scholar
  11. 11.
    Weichselbaum, A.: Wien. Klin. Wochenschr., 24:153, 1911.Google Scholar
  12. 12.
    Moritz, A. R., and Oldt, M. B.: Am. J. Pathol, 13:679, 1937.PubMedGoogle Scholar
  13. 13.
    Neumann, F.: Cited by E. J. Kraus: In: Handbuch der Spez. Pathol. Pathol. Anat., Vol. V/2. Edited by F. Henke and O. Lubarsch. Springer, Berlin, 1929, p. 689.Google Scholar
  14. 14.
    Lazarus, S. S., and Volk, B. W.: The Pancreas in Human and Experimental Diabetes. Grune & Stratton, New York, 1962, p. 196.Google Scholar
  15. 15.
    Maclean, N., and Ogilvie, R. F.: Diabetes, 4:367, 1955.PubMedGoogle Scholar
  16. 16.
    Gepts, W.: Ann. Soc. R. Sci. Med Nat. Bruxelles, 10:5, 1957.Google Scholar
  17. 17.
    Gepts, W.: Endokrinologie, 36:185, 1958.PubMedGoogle Scholar
  18. 18.
    Bell, E. T.: Diabetes, 2:376, 1953.PubMedGoogle Scholar
  19. 19.
    Wrenshall, G. A., Bogoch, A., and Ritchie, R. C.: Diabetes, 1:87, 1952.PubMedGoogle Scholar
  20. 20.
    Wrenshall, G. A., Hartroft, W. S., and Best, C. H.: Diabetes, 3:444, 1954.PubMedGoogle Scholar
  21. 21.
    Bornstein, J.: J. Endocrinol, 7:59, 1953.Google Scholar
  22. 22.
    Bornstein, J.: Diabetes, 2:23, 1953.PubMedGoogle Scholar
  23. 22a.
    Yalow, R. S., and Berson, S. A.: Clin. Invest., 39:1157, 1960.Google Scholar
  24. 23.
    Houssay, B. A.: Am. J. Med Sci., 193:581, 1937.Google Scholar
  25. 24.
    Long, C. N. H., and Lukens, F. D. W.: J. Exp. Med, 63:465, 1936.PubMedGoogle Scholar
  26. 25.
    Young, F. G.: Lancet, 2:372, 1937.Google Scholar
  27. 26.
    Gundersen, E.: J. Infect. Dis., 41:197, 1927.Google Scholar
  28. 27.
    Gamble, D. R., Kinsley, M. L., Fitzgerald, M. G., Bolten, R., and Taylor, K. W.: Br. Med. J., 3:627, 1969.PubMedGoogle Scholar
  29. 28.
    Pav, J., Jezkova, Z., and Skrha, F.: Lancet, 3:221, 1963.Google Scholar
  30. 29.
    Chetty, M. P., and Watson, K. C.: Lancet, 1:67, 1965.PubMedGoogle Scholar
  31. 29a.
    Roth, J., Kahn, C. R., Lesniak, M. A., Gorden, P., deMeyts, P., Megyest, K., Neville, D. M., Jr., Gavin, J. R., III, Soil, A. H. Freychet, P. Goldfine, I. D. Bar, R. S., and Archer, J. A.: Recent Prog. Horm. Res., 31:95, 1975.Google Scholar
  32. 30.
    Vallance-Owen, J.: Diabetes, 13:241, 1964.PubMedGoogle Scholar
  33. 31.
    Antoniades, H. N., Gundersen, K., Beigelman, P. M., Pyle, H. M., and Bougas, J. A.: Diabetes, 11:261, 1962.PubMedGoogle Scholar
  34. 32.
    Unger, R. H., and Orci, L.: Lancet, 1:14, 1975.PubMedGoogle Scholar
  35. 32a.
    Warren, S., LeCompte, F. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Fhiladelphia, 1966.Google Scholar
  36. 32b.
    Gepts, W.: In: The Islets of Langerhans. Edited by S. J. Cooperstein and D. Watkins. Academic Press, New York, 1981, p. 321.Google Scholar
  37. 33.
    Weichselbaum, A.: Sitzungsber. Akad. Wiss. Wien Math. Naturwiss. Kl, 119:73, 1910.Google Scholar
  38. 34.
    Herxheimer, G.: Verh. Dtsch. Ges. Verdau. Stoffwechselkr., 11:112, 1933.Google Scholar
  39. 35.
    von Halasz, A.: Wien. Klin. Wochenschr., 22:1481, 1909.Google Scholar
  40. 36.
    Seyfarth, C.: Muench. Med Wochenschr., 67:617, 1920.Google Scholar
  41. 37.
    Terplan, K.: Fersonal communication to Warren, S. LeCompte, P. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Fhiladelphia, 1966, p. 113.Google Scholar
  42. 38.
    Maclean, N., Robertson, F., and Ogilvie, R. F.: Diabetes, 8:83, 1959.PubMedGoogle Scholar
  43. 39.
    Kraus, E. J.: In: Handbuch der Speziellen Pathologischen Anatomie und Histologie, Vol. V/2. Edited by F. Henke and O. Lubarsch. Springer, Berlin, 1929, pp. 662.Google Scholar
  44. 40.
    Vartiainen, L: Acta Med. Scand, 118:536, 1944.Google Scholar
  45. 41.
    Terbrüggen, A.: Virchows Arch., 315:407, 1948.PubMedGoogle Scholar
  46. 42.
    Warren, S., and LeCompte, F. M.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1952, p. 73.Google Scholar
  47. 43.
    Lazarus, S. S., and Volk, B. W.: The Pancreas in Human and Experimental Diabetes. Grüne & Stratton, New York, 1962, p. 196.Google Scholar
  48. 44.
    Hansemann, D.: Z. Klin. Med., 26:191, 1894.Google Scholar
  49. 45.
    Simmonds, F.: Dtsch. Med Wochenschr., 38:1020, 1912.Google Scholar
  50. 46.
    Opie, E. L.: J. Exp. Med, 5:397, 1900–01.PubMedGoogle Scholar
  51. 47.
    Weichselbaum, A., and Stangl, E.: Wien. Klin. Wochenschr., 14:968, 1901.Google Scholar
  52. 48.
    Seyfarth, C: Verh. Kongr. Inn. Med., 32:178, 1920.Google Scholar
  53. 49.
    Allen, F. M.: J. Metab. Res., 1:5, 1922.Google Scholar
  54. 50.
    Lazarus, S. S., and Volk, B. W.: The Pancreas in Human and Experimental Diabetes. Grüne & Stratton, New York, 1962, p. 209.Google Scholar
  55. 51.
    Ehrlich, J. C, and Ratner, I. M.: Am. J. Pathol., 38:49, 1961.PubMedGoogle Scholar
  56. 52.
    Bell, E. T.: Diabetes, 1:341, 1952.PubMedGoogle Scholar
  57. 53.
    Seifert, G.: Verh. Dtsch. Ges. Pathol, 18:50, 1959.Google Scholar
  58. 54.
    Warren, S., LeCompte, F. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Fhiladelphia, 1966, p. 60.Google Scholar
  59. 55.
    Legg, M. A.: Quoted in: Warren, S., LeCompte, F. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Fhiladelphia, 1966, p. 60.Google Scholar
  60. 56.
    Ohlmacher, J. C: Am. J. Med Sci., 128:287, 1904.Google Scholar
  61. 57.
    Saltykow, O.: Corresp. Bl Schweiz. Aerzte, 39:625, 1909.Google Scholar
  62. 58.
    Milne, L. S., and Peters, H. L.: J. Med Res., 26:405, 1912.PubMedGoogle Scholar
  63. 59.
    Wright, A. W.: Am. J. Pathol, 3:461, 1927.PubMedGoogle Scholar
  64. 60.
    Ahronheim, J. H.: Am. J. Pathol, 19:873, 1943.PubMedGoogle Scholar
  65. 61.
    Arey, J. B.: Arch. Pathol, 36:32, 1943.Google Scholar
  66. 62.
    Warren, S.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1938, p. 31.Google Scholar
  67. 63.
    Bell, E. T.: Am. J. Pathol, 35:801, 1959.PubMedGoogle Scholar
  68. 64.
    Bell, E. T.: Diabetes Mellitus. Thomas, Springfield, III., 1960, p. 55.Google Scholar
  69. 65.
    Hartroft, W. S.: Diabetes, 5:98, 1956.PubMedGoogle Scholar
  70. 66.
    Opie, E. L: J. Exp. Med, 5:527, 1900–01.PubMedGoogle Scholar
  71. 67.
    Mallory, F. B.: The Principles of Pathologic Histology. Saunders, Philadelphia, 1914, p. 521.Google Scholar
  72. 68.
    Gomori, G.: Arch. Pathol, 36:217, 1943.Google Scholar
  73. 69.
    Bloom, F.: N. Engl J. Med., 217:395, 1937.Google Scholar
  74. 70.
    Van Beek, C C: Ned. Tijdschr. Geneeskd., 83:646, 1939.Google Scholar
  75. 71.
    Gellerstedt, N.: Beitr. Pathol Anat. Allg. Pathol, 101:1, 1938.Google Scholar
  76. 72.
    Schwartz, P.: Trans. N.Y. Acad. Sci., 27:393, 1965.PubMedGoogle Scholar
  77. 73.
    Lacy, P. E.: In: Aetiology of Diabetes and Its Complications. Edited by M. P. Cameron and M. O’Connor. Little, Brown, Boston, 1964, p. 84.Google Scholar
  78. 74.
    Porta, E. A., Yerry, Y. R., and Scott, R. F.: Am. J. Pathol., 41:623, 1962.PubMedGoogle Scholar
  79. 75.
    Kawanishi, H., Akazawa, Y., and Machii, B.: Acta Pathol., Jpn., 16:177, 1966.Google Scholar
  80. 76.
    Westermark, P.: Virchows Arch. A, 359:1, 1973.Google Scholar
  81. 77.
    Rinehart, J. F., Toreson, W. E., and Abul-Haj, S. K.: Am. J. Med., 17:124, 1954.Google Scholar
  82. 78.
    Hartroft, W. S.: Diabetes, 5:98, 1956.PubMedGoogle Scholar
  83. 79.
    Pearse, A. G. E., Ewen, S. W. B., and Polak, J. M.: Virchows Arch. B, 10:93, 1972.Google Scholar
  84. 80.
    Westermark, P.: Histochemistry, 38:27, 1974.Google Scholar
  85. 81.
    Westermark, P.: Virchows Arch. A, 373:161, 1977.Google Scholar
  86. 82.
    Westermark, P., Grimelius, L., Polak, J. M., Larsson, L.-L, Van Norden, S., Wilander, E., and Pearse, A. G. E.: Lab. Invest., 37:212, 1977.PubMedGoogle Scholar
  87. 82a.
    Westermark, P., and Wilander, E.: Diabetologia, 24:342, 1983.PubMedGoogle Scholar
  88. 83.
    Westermark, P., and Wilander, E.: Diabetologia, 15:417, 1978.PubMedGoogle Scholar
  89. 83a.
    Schneider, H. M., Störkei, F. S., and Will, W.: Dtsch. Med. Wochenschr., 105:1143, 1980.PubMedGoogle Scholar
  90. 83b.
    Schneider, H. M., Störkei, F. S., and Will, W.: Pathol. Res. Pract., 170:180, 1980.PubMedGoogle Scholar
  91. 83c.
    Maloy, A. L., Longnecker, D. S., and Greenberg, E. R.: Hum. Pathol., 12:917, 1981.PubMedGoogle Scholar
  92. 83d.
    Longnecker, D. S.: Human. Pathol., 13:872, 1982.Google Scholar
  93. 84.
    Olsen, T. S.: Acta Pathol. Microbiol. Scand Sect. A, 86:361, 1978.Google Scholar
  94. 85.
    Herxheimer, G.: In: Handbuch der Inneren Sekretion. Edited by M. Hirsch. Deutsche Gesellschaft fur Verdauungs-und Stoffwechsel krankheiten, Berlin, 1925.Google Scholar
  95. 86.
    Seyfarth, C.: Muenchener Medizinische Wochenscrift, 67:617, 1920.Google Scholar
  96. 87.
    Moschcowitz, E.: Ann. Intern. Med., 34:1137, 1951.PubMedGoogle Scholar
  97. 88.
    Warren, S., LeCompte, P. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1966, p. 106.Google Scholar
  98. 89.
    Lazarus, S. S., and Volk, B. W.: The Pancreas in Human and Experimental Diabetes. Grune & Stratton, New York, 1962, p. 199.Google Scholar
  99. 90.
    Warren, S., LeCompte, P. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1966, p. 102.Google Scholar
  100. 91.
    Sauerbeck, E.: Ergeb. Allg. Pathol. Pathol. Anat., 8:538, 1902.Google Scholar
  101. 92.
    Lazarus, S. S., and Volk, B. W.: The Pancreas in Human and Experimental Diabetes. Grune & Stratton, New York, 1962, p. 202.Google Scholar
  102. 93.
    Hultquist, G. T., and Olding, L. B.: Lancet, 2:1016, 1975.Google Scholar
  103. 94.
    Otani, S.: Am. J. Pathol., 3:1, 1927.PubMedGoogle Scholar
  104. 95.
    Comfort, M. W., Gambill, E. E., and Baggenstoss, A. H.: Gastroenterology, 6:239, 1946.PubMedGoogle Scholar
  105. 96.
    Maimon, S. N., Kirsner, J. B., and Palmer, W. L.: Arch. Intern. Med, 81:56, 1948.Google Scholar
  106. 97.
    Popper, H.: Gastroenterology, 19:183, 1952.Google Scholar
  107. 98.
    Robbins, S. L.: Textbook of Pathology. Saunders, Philadelphia, 1957, p. 870.Google Scholar
  108. 99.
    Blumenthal, H. T., and Probstein, J. G.: Pancreatitis: A Clinical-Pathologic Correlation. Thomas, Springfield, III., 1959.Google Scholar
  109. 100.
    Hranilovich, G. T., and Baggenstoss, A. H.: Arch. Pathol., 55:443, 1953.Google Scholar
  110. 101.
    Herxheimer, G.: Virchows Arch., 183:228, 1906.Google Scholar
  111. 102.
    Gruber, G.: In: Handb. Pathol. Pathol. Anat., Vol. V/2. Edited by F. Henke and O. Lubarsch. Springer, Berlin, 1929, p. 211.Google Scholar
  112. 103.
    Dieckhoff, C.: Beitr. PathoL Anat. Pankreas Med. Inaug.-Diss., Rostock, 1894.Google Scholar
  113. 104.
    Priesel, R.: Frankf Z. Pathol., 26:453, 1922.Google Scholar
  114. 105.
    Lang, F. J.: Virchows Arch., 257:246, 1925.Google Scholar
  115. 106.
    Lazarus, S. S., and Volk, B. W.: The Pancreas in Human and Experimental Diabetes. Grune & Stratton, New York, 1962, p. 204.Google Scholar
  116. 107.
    Heiberg, K. A.: Zentralbl. Allg. Pathol. Pathol. Anat., 221:532, 1911.Google Scholar
  117. 108.
    Fischer, B.: Frankf Z. Pathol., 17:218, 1915.Google Scholar
  118. 108a.
    Cotelingam, J. D., and Hellstrom, H. R.: Diabetes, 27:620, 1978.PubMedGoogle Scholar
  119. 109.
    Nakamura, N.: Arch. Pathol. Anat., 253:286, 1924.Google Scholar
  120. 110.
    Martius, K.: Frankf Z. Pathol., 17:276, 1915.Google Scholar
  121. 111.
    Conroy, M. J.: Metab. Res., 2:367, 1922.Google Scholar
  122. 112.
    Karakascheff, K. I.: Dtsch. Arch. Klin. Med, 82:60, 1904–1905.Google Scholar
  123. 113.
    Thoinot, L., and Delamare, G.: Arch. Med. Exp. Anat. Pathol., 19:176, 1907.Google Scholar
  124. 114.
    Sauerbeck, E.: Virchows Arch., 177:1, 1904.Google Scholar
  125. 115.
    Gomori, G.: Am. J. Pathol., 17:395, 1941.PubMedGoogle Scholar
  126. 116.
    Hartroft, W. S.: Proc. Am. Diabetes Assoc., 10:46, 1950.Google Scholar
  127. 117.
    Warren, S., LeCompte, P. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1966, p. 73.Google Scholar
  128. 118.
    Kraus, E. J.: Virchows Arch., 247:1, 1923.Google Scholar
  129. 119.
    Toreson, W. E.: Am. J. Pathol., 27:327, 1951.PubMedGoogle Scholar
  130. 120.
    Lazarus, S. S., and Volk, B. W.: The Pancreas in Human and Experimental Diabetes. Grune & Stratton, New York, 1962, p. 102.Google Scholar
  131. 121.
    Volk, B. W., and Lazarus, S. S.: Diabetes, 13:60, 1964.PubMedGoogle Scholar
  132. 122.
    Gepts, W.: In: The Structure and Metabolism of the Pancreatic Islets. Edited by S. Brolin, B. Hellman, and H. Knutson. Macmillan Co., New York, 1964, p. 513.Google Scholar
  133. 123.
    Gepts, W.: Diabetes, 14:619, 1965.PubMedGoogle Scholar
  134. 124.
    Williamson, J. R., and Lacy, P. E.: Arch. Pathol, 72:637, 1961.PubMedGoogle Scholar
  135. 125.
    Volk, B. W., and Lazarus, S. S.: Diabetes, 12:162, 1963.Google Scholar
  136. 126.
    Lazarus, S. S., and Volk, B. W.: Arch. Pathol, 71:44, 1961.PubMedGoogle Scholar
  137. 127.
    Bastenie, P.: Cortico-Surrénale et Diabète Humain. Masson, Paris, 1956, p. 148.Google Scholar
  138. 128.
    Lazarus, S. S., and Volk, B. W.: The Pancreas in Human and Experimental Diabetes. Grune & Stratton, New York, 1962, p. 106.Google Scholar
  139. 129.
    Gomori, G.: Bull N. Y. Acad. Med., 21:99, 1945.PubMedGoogle Scholar
  140. 130.
    Weichselbaum, A.: Sitzungsber. Akad. Wiss. Wien Math. Naturwiss. Kl 117:211, 1908.Google Scholar
  141. 131.
    Warren, S., LeCompte, P. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1966, p. 80.Google Scholar
  142. 132.
    Eder, M.: Beitr. Pathol Anat. Allg Pathol, 115:157, 1955.Google Scholar
  143. 133.
    Cecil, R. L.: J. Exp. Med., 14:500, 1911.PubMedGoogle Scholar
  144. 134.
    Ogilvie, R. F.: In: Aetiology of Diabetes and Its Complications. Edited by M. P. Cameron, and M. O’Connor. Little, Brown, Boston, 1964, p. 69.Google Scholar
  145. 135.
    Ogilvie, R. F.: Edinburgh Med. J., 51:460, 1944.Google Scholar
  146. 136.
    LeCompte, P. M.: In: Diabetes. Edited by R. H. Williams. Hoeber, New York, 1960, p. 309.Google Scholar
  147. 137.
    Hüttl, T.: Beitr. Z. Klin. Chir., 163:206, 1936.Google Scholar
  148. 138.
    Warren, S., LeCompte, P. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1966, p. 80.Google Scholar
  149. 139.
    von Meyenburg, H.: Schweiz. Med. Wochenschr., 21:554, 1940.Google Scholar
  150. 140.
    Deconinck, J., Potvliege, P. R., and Gepts, W.: In: Handbook of Physiology, Sect. 7, Vol. 1. Edited by R. O. Greep, E. B. Astwood, D. F. Steiner, N. Freinkel, and S. R. Geiger. Williams & Wilkins, Baltimore, 1972, p. 295.Google Scholar
  151. 141.
    LeCompte, P. M.: Arch. Pathol, 66:450, 1958.Google Scholar
  152. 142.
    Warren, S.: J. Am. Med. Assoc., 88:99, 1927.Google Scholar
  153. 143.
    Stansfield, O., and Warren, S.: N. Engl J. Med., 198:686, 1928.Google Scholar
  154. 144.
    LeCompte, P. M., Steinke, J., Soeldner, J. S., and Renold, A. E.: Diabetes, 15:586, 1966.PubMedGoogle Scholar
  155. 145.
    Barboni, E., and Manocchio, I.: Arch. Vet. Ital, 13:411, 1962.Google Scholar
  156. 146.
    Gamble, D. R., Kinsley, M. L., Fitzgerald, M. G., Bolton, R., and Taylor, K. W.: Br. Med. J., 3:627, 1969.PubMedGoogle Scholar
  157. 147.
    Renold, A. E., Soeldner, J. S., and Steinke, J.: In: Aetiology of Diabetes and Its Complications. Edited by M. P. Cameron, and M. O’Connor. Little, Brown, Boston, 1964, p. 122.Google Scholar
  158. 148.
    Toreson, W. E., Lee, J. C, and Grodsky, G. M.: Am. J. Pathol, 52:1099, 1968.PubMedGoogle Scholar
  159. 149.
    Lazarus, S. S., and Volk, B. W.: The Pancreas in Human and Experimental Diabetes. Grune & Stratton, New York, 1962, p. 212.Google Scholar
  160. 150.
    Gutman, C: Virchows Arch. A, 172:493, 1903.Google Scholar
  161. 151.
    Schmidt, M. B.: Muench. Med Wochenschr., 49:51, 1959.Google Scholar
  162. 152.
    Dogiel, A. S.: Arch. Anat. Entwicklungsgesch., 2:117, 1893.Google Scholar
  163. 153.
    Weichselbaum, A., and Stangl, E.: Wien. Klin. Wochenschr., 15:969, 1902.Google Scholar
  164. 154.
    Symmers, D.: Arch. Intern. Med., 3:379, 1909.Google Scholar
  165. 155.
    Wilder, R. M.: South. Med. J., 19:241, 1926.Google Scholar
  166. 156.
    Gibb, W. F., and Logan, V. W.: Arch. Intern. Med., 43:376, 1929.Google Scholar
  167. 157.
    Hartroft, W. B.: In: Diabetes. Edited by R. H. Williams. Hoeber, New York, 1960, p. 350.Google Scholar
  168. 158.
    Like, A. A.: Lab Invest., 16:937, 1967.PubMedGoogle Scholar
  169. 159.
    Deconinck, J. F., Potvliege, P. R., and Gepts, W.: Diabetologia, 7:266, 1971.PubMedGoogle Scholar
  170. 160.
    Deconinck, J. F., van Assche, F. A., Potvliege, P. R., and Gepts, W.: Diabetologia, 8:326, 1972.PubMedGoogle Scholar
  171. 161.
    Warren, S., LeCompte, P. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1966, p. 62.Google Scholar
  172. 162.
    Ssobolew, L. W.: Virchows Arch., 168:91, 1902.Google Scholar
  173. 163.
    Herzog, M.: Virchows Arch., 168:83, 1902.Google Scholar
  174. 164.
    Moore, R. A.: Am. J. Dis. Child., 52:627, 1936.Google Scholar
  175. 165.
    Dieckhoff, G.: Beitr. Z. Wiss. Med. Festschrift. Thierfelder, Leipzig, 1895, p. 97.Google Scholar
  176. 166.
    Bence, J.: Wien. Klin. Wochenschr., 20:721, 1907.Google Scholar
  177. 167.
    Potter, N. B., and Milne, L. S.: Am. J. Med Sci., 143:46, 1911.Google Scholar
  178. 168.
    Gepts, W.: In: Handbook of Diabetes Mellitus, Vol. 2. Edited by E. F. Pfeiffer. Lehmanns, Munich, 1971, p. 3.Google Scholar
  179. 169.
    Heiberg, K. A.: Anat. Am., 29:49, 1906.Google Scholar
  180. 170.
    Neumann, F.: Cited by E. J. Kraus: In: Handb. Spez. Pathol. Pathol. Anat., Vol. V/2. Edited by F. Henke and O. Lubarsch. Springer, Berlin, 1929, p. 689.Google Scholar
  181. 171.
    Susman, W.: J. Clin. Endocrinol, 2:97, 1942.Google Scholar
  182. 172.
    Hellman, B.: Acta Pathol. Microbiol. Scand, 51:95, 1961.PubMedGoogle Scholar
  183. 173.
    Hellman, B., and Angervale, L.: Acta Pathol. Microbiol. Scand, 53:230, 1961.PubMedGoogle Scholar
  184. 173a.
    Rahier, J., Goebbels, R. M., and Henquin, J. C: Diabetologia, 24:1366, 1983.Google Scholar
  185. 174.
    Creutzfeldt, W.: Beitr. Pathol. Anat. Allg Pathol., 113:133, 1953.Google Scholar
  186. 175.
    Creutzfeldt, W.: Zentralbl. Inn. Med, 1956.Google Scholar
  187. 176.
    Creutzfeldt, W., and Theodossiou, A.: Beitr. Pathol. Anat. Allg. Pathol, 117:235, 1957.Google Scholar
  188. 177.
    Gomori, G.: Bull N. Y. Acad Med, 21:99, 1945.PubMedGoogle Scholar
  189. 178.
    Ferner, H.: Z. Mikrosk. Anat. Forsch., 44:451, 1938.Google Scholar
  190. 179.
    Ferner, H.: Virchows Arch., 309:87, 1942.Google Scholar
  191. 180.
    Ferner, H.: Dtsch. Z. Verdau. Stoffwechselkr., 6:21, 1942.Google Scholar
  192. 181.
    Ferner, H.: Dtsch. Med Wochenschr., 72:540, 1947.PubMedGoogle Scholar
  193. 182.
    Ferner, H.: Virchows Arch., 319:390, 1951.PubMedGoogle Scholar
  194. 183.
    Ferner, H.: Das Inselsystem des Pankreas. Thieme Verlag, Stuttgart, 1952, p. 149.Google Scholar
  195. 184.
    Hess, W.: Schweiz. Z. Pathol Bakteriol, 9:46, 1946.PubMedGoogle Scholar
  196. 185.
    von Meyenburg, H.: Schweiz. Med. Wochenschr., 76:207, 1946.Google Scholar
  197. 186.
    Hultquist, G., Dahlen, M., and Helander, C. G.: Schweiz. Z. Pathol Bakteriol, 11:570, 1948.Google Scholar
  198. 187.
    Terbrüggen, A.: Klin. Wochenschr., 24–25:434, 1947.Google Scholar
  199. 188.
    Seifert, G.: Virchows Arch., 325:379, 1954.PubMedGoogle Scholar
  200. 189.
    Bürkl, W.: Acta Anat., 12:358, 1951.PubMedGoogle Scholar
  201. 190.
    Bürkl, W., and Kovac, W.: Mikroskopie, 6:283, 1951.PubMedGoogle Scholar
  202. 191.
    Warren, S., LeCompte, P. M., and Legg, M. A.: The Pathology of Diabetes Mellitus. Lea & Febiger, Philadelphia, 1966, p. 97.Google Scholar
  203. 192.
    Ogilvie, R. F.: J. Pathol Bacteriol, 37:473, 1933.Google Scholar

Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • Bruno W. Volk
    • 1
  • Klaus F. Wellmann
    • 2
  1. 1.Department of PathologyUniversity of California Irvine Medical CenterOrangeUSA
  2. 2.Department of PathologyState University of New York, Downstate Medical CenterBrooklynUSA

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