Colon pp 253-273 | Cite as

Colonic Adaptation

  • H. Menge
  • J. W. L. Robinson
Part of the Topics in Gastroenterology book series (TGEN)


The mucosa of the colon is generally considered a less complex structure than that of the small intestine. It is often described as a flat surface containing large numbers of closely spaced crypts,1 but in this way the role of the haustra in causing a huge increase in the absorptive surface is neglected. In the rat, mucosal folds, presumably equivalent to the haustra of the human colon, assume varying forms at the different levels of the colon (Figs. 1–3); they are not easily quantified on histological preparations, particularly in the cecum and ascending colon, where cutting the tissue strictly perpendicular to the folds is especially difficult. For this reason, these structures tend to be ignored in the description of adaptive changes in this organ.


Colonic Mucosa Blind Loop Crypt Cell Proliferation Mucosal Surface Area Absorptive Flux 
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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • H. Menge
    • 1
  • J. W. L. Robinson
    • 2
  1. 1.Abteilung für Innere Medizin mit Schwerpunkt GastroenterologieKlinikum Steglitz der Freien UniversitätBerlinFederal Republic of Germany
  2. 2.Département de Chirurgie Expérimentale, Centre HospitalierUniversitaire VaudoisLausanneSwitzerland

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