Ultrastructure of Amyloid Fibrils in Alzheimer’s Disease and Down’s Syndrome

  • Taihei Miyakawa
  • Shoichi Katsuragi
  • Kenjiro Watanabe


Ultrastructure of amyloid fibrils in senile plaques of the brains with Alzheimer’s disease and adult Down’s syndrome has not yet been reported in detail. In the present study, in addition to the electron microscopic examination of tissue specimens, replicas of amyloid fibrils made by a quick freezing method ( Heuser et al. 1979 ) were examined.


Prion Protein Senile Plaque Amyloid Fibril Scrapie Prion Protein Quantal Transmitter Release 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Taihei Miyakawa
    • 1
  • Shoichi Katsuragi
    • 1
  • Kenjiro Watanabe
    • 1
  1. 1.Department of neuropsychiatryKumamoto University Medical SchoolHonjo-Machi, Kumamoto, 860Japan

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