Clinicopathological Studies on Nephropathy of Familial Amyloid Polyneuropathy in Japan

  • Nobuo Itoh
  • Hidekazu Shigematsu
  • Shu-ichi Ikeda
  • Hisao Oguchi


In Japan, Araki et al.1 first reported patients with familial amyloid polyneuropathy (FAP) in Kumamoto Prefecture where is one Japanese focus of the disease, and showed their clinical features identical to those of Portuguese FAP (Type I) first described by Andrade2. There is another focus of Japanese FAP in Nagano Prefecture reported by Kito et al3.


Amyloid Fibril Heavy Proteinuria Chronic Pyelonephritis Familial Amyloid Polyneuropathy Familial Amyloidotic Polyneuropathy 


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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Nobuo Itoh
    • 1
  • Hidekazu Shigematsu
    • 1
  • Shu-ichi Ikeda
    • 1
  • Hisao Oguchi
    • 1
  1. 1.Departments of Pathology and Internal MedicineShinshu University School of MedicineMatsumoto 390Japan

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