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Familial Amyloid Polyneuropathy: A Clinical Scale for the Evaluation of the Peripheral Neuropathy

  • Eugénia Macedo
  • Paula Coutinho
  • Rosa Morais
  • Eduarda Matos
Chapter

Abstract

A considerable progress has been made in the recent past in understanding Familial Amyloid Polyneuropathy (FAP) which expectedly will contribute towards new therapeutical trials. Besides, the heightened concern for a disease whose progressive course leads to complete disability and death in about 10 years must also motivate therapeutical attempts. Under these circumstances, the need for a statistically tested scale as an empirical instrument for evaluating the trials seems quite justified. Such scales exist for other neurological disorders such as Parkinson disease1 and multiple sclerosis2.

Keywords

Autonomic Neuropathy Motor Neuropathy Familial Amyloid Polyneuropathy Partial Score Heighten Concern 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    M. D. Yahr, R. Duvoisin, L. Schear, S. Myrne, R. S. Barret, Hoehn and E. Margaret, Treatment of Parkinsonism with levodopa, Arch. Neurol., 21: 343 (1969).CrossRefGoogle Scholar
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    J. F. Kurtzke, On the evaluation of disability in multiple sclerosis, Neurology (Minneap.), 11: 686 (1961).CrossRefGoogle Scholar
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    C. Andrade, A peculiar form of peripheral neuropathy — familial atypical generalized amyloidosis with special involvment of peripheral nerves, Brain, 75: 408 (1952).CrossRefGoogle Scholar
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    P. Coutinho, A. Martins da Silva, J. Lopes Lima, A. Resende Barbosa, Forty years of experience with type I amyloid neuropathy (review of 483 cases), in: “Amyloid and Amyloidosis”, G. G. Glenner, P. Pinho e Costa & Falcão de Freitas, eds., Excerpta Medica, Amsterdam (1980).Google Scholar

Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Eugénia Macedo
    • 1
  • Paula Coutinho
    • 1
  • Rosa Morais
    • 2
  • Eduarda Matos
    • 2
  1. 1.Serviço de NeurologiaHospital Geral de Santo AntónioPortoPortugal
  2. 2.Departamento de Saúde Comunitária, Instituto de Ciências BiomédicasUniversidade do PortoPortugal

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