Systemic Amyloidosis: Tissue Specific Variability in the Primary Structure of Amyloid Proteins

  • Mordechai Pras


Amyloidosis comprises a heterogenous group of diseases, characterized by the deposition of fibrillar proteins in various tissues and organs. Amyloid proteins consist of a number of chemically diverse polypeptides of low molecular weight that share several characteristic tinctorial properties, B-pleated sheet conformation and solubility in low ionic strength solutions, which facilitates their isolation from other tissue constituents (1,2).


Familial Mediterranean Fever Amyloid Fibril Amyloid Protein Free Light Chain Systemic Amyloidosis 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Mordechai Pras
    • 1
  1. 1.Heller Institute of Medical ResearchSheba Medical CenterTel-HashomerIsrael

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