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Is the Homozygous State for Hereditary Amyloid Neuropathy (HAN) — Type I (Portuguese, Andrade) Incompatible with Early Intrauterine Life?

  • Jorge Sequeiros
  • Alda Sousa
Chapter

Abstract

In a classic definition, an autosomal dominant trait was one that would show the same effect in either the homozygous, or the heterozygous state; nevertheless, experience has been accumulating in medical genetics of a number of autosomal dominant disorders where a dose effect in homozygosity is suspected 1–6, including the Finnish type of hereditary amyloid neuropathy (HAN — type IV)7.

Keywords

Marfan Syndrome Autosomal Dominant Disorder Autosomal Dominant Trait Familial Amyloidotic Polyneuropathy Unaffected Child 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Jorge Sequeiros
    • 1
    • 2
    • 3
  • Alda Sousa
    • 3
  1. 1.Centro de Estudos da Paramiloidose AntónioPortugal
  2. 2.Hospital Geral de Santo AntónioPortugal
  3. 3.Instituto de Ciências Biomédicas de Abel SalazarUniversidade do PortoPortugal

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