RFLP Analysis of Mutated Transthyretin in Vitreous Amyloidosis

  • O. Sandgren
  • G. Holmgren
  • E. Lundgren
  • L. Steen


Amyloid deposits of the vitreous are usually associated with familial amyloidosis of the neuropathic type (FAP) and has been reported in the Portuguese as well as the Japanese and the Swedish forms of FAP type 1. Vitreous opacities are also found in the Jewish FAP type 1 and in the Indiana/Swiss FAP type 2. However sporadic cases with vitreous opacities and cases without systemic disease have been reported.


Amyloid Deposit RFLP Marker Familial Amyloidotic Polyneuropathy Vitreous Opacity Village Type 


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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • O. Sandgren
    • 1
  • G. Holmgren
    • 2
  • E. Lundgren
    • 3
  • L. Steen
    • 4
  1. 1.Departments of OphthalmologyUniversity of UmeåSweden
  2. 2.Clinical GeneticsUniversity of UmeåSweden
  3. 3.The Unit for Applied Cell and Molecular BiologyUniversity of UmeåSweden
  4. 4.Internal MedicineUniversity of UmeåSweden

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