Insulin for Nausea in Familial Amyloid Polyneuropathy

  • Shin’ichi Shoji
  • Junko Kamijo
  • Nobuo Yanagisawa


In a patient with familial amyloid polyneuropathy there was a significant negative correlation between the degree of nausea/vomiting and urinary epinephrine output. In this patient infusion of epinephrine could stop strong continuous nausea. The injection of insulin, which stimulates epinephrine secretion from the adrenal glands by causing hypoglycemia, was found to be capable of stopping strong continuous nausea not only in this patient but also in 26 other patients with gastrointestinal disorders or early pregnancy.


Early Pregnancy Insulin Injection Plasma Epinephrine Drip Infusion Pepsin Secretion 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Shin’ichi Shoji
    • 1
  • Junko Kamijo
    • 1
  • Nobuo Yanagisawa
    • 1
  1. 1.Department of MedicneShinshu University, School of MedicneMatsumotoJapan

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