Advertisement

Amyloid Localized to Tenosynovium at Carpal Tunnel Release: The Natural History of 124 Cases

  • Robert A. Kyle
  • Stanley G. Eilers
  • Ronald L. Linscheid
  • Thomas A. Gaffey
Chapter

Abstract

The carpal tunnel syndrome results from entrapment of the median nerve from a variety of systemic diseases including rheumatoid arthritis, myxedema, systemic lupus erythematosus, acromegaly, diabetes, and amyloidosis as well as dislocation or fracture of the carpal bones or osteophytes. The carpal tunnel syndrome is present in about one-fourth of patients at the time of diagnosis of primary systemic amyloidosis (AL) (Kyle and Greipp, 1983). The incidence of amyloid deposits in the flexor synovialis or the transverse carpal ligament of patients with carpal tunnel syndrome is low—7% in one report (Yamaguchi et al, 1965) and 1% in another (Bastian, 1974). The clinical significance of amyloid in the tenosynovium or carpal ligament in the absence of systemic amyloidosis is unknown. This prompted us to review our experience.

Keywords

Median Nerve Carpal Tunnel Syndrome Abdominal Aortic Aneurysm Carpal Tunnel Amyloid Deposit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Kyle, R. A. and Greipp, P. R., 1983, Amyloidosis (AL). Clinical and laboratory features of 229 cases. Mayo Clin. Proc., 58:665.Google Scholar
  2. Yamaguchi, D. M., Lipscomb, P. R., and Soule, E. H., 1965, Carpal tunnel syndrome. Minn. Med., 48:22.Google Scholar
  3. Bastian, F. O., 1974, Amyloidosis and the carpal tunnel syndrome. Am. J. Pathol., 61:711.Google Scholar
  4. Paget, J., 1854, “Lectures on Surgical Pathology,” Lindsay and Blakiston, Philadelphia.Google Scholar
  5. Hunt, J. R., 1911, The thenar and hypothenar types of neural atrophy of the hand. Am. J. Med. Sci., 141:224.CrossRefGoogle Scholar
  6. Marie et Foix, P., 1913. Atrophie isolée de l’éminence thénar d’origine névritique. Role du ligament annulaire antérieur du carpe dans la pathogénie de lalésion. Rev. Neurol., 26:647.Google Scholar
  7. Woltman, H. W., 1941, Neuritis associated with acromegaly. Arch. Neurol. Psychiatr., 45:680.CrossRefGoogle Scholar
  8. Cannon, B. W. and Love, J. G., 1946, Tardy median palsy; median neuritis; median thenar neuritis amendable to surgery. Surgery, 20:210.Google Scholar
  9. Brain, W. R., Wright, A. D., Wilkinson, M., 1947, Spontaneous compression of both median nerves in the carpal tunnel. Lancet, 1:277.CrossRefGoogle Scholar
  10. Phalen, G. S., 1966, The carpal-tunnel syndrome. Seventeen years’ experience in diagnosis and treatment of six hundred fifty-four hands. J. Bone Joint Surg., 48-A:211.Google Scholar

Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Robert A. Kyle
    • 1
  • Stanley G. Eilers
    • 1
  • Ronald L. Linscheid
    • 1
  • Thomas A. Gaffey
    • 1
  1. 1.Mayo Medical SchoolRochesterUSA

Personalised recommendations