Immunological Examination of Senile Amyloidosis of the Temporal Artery
Immunohistochemical examination of the amyloid deposits of the internal elastic laminae of temporal arteries taken from aged subjects showed strong reactions reflecting the presence of P-component in relation to the amyloid deposits but not the elastic lamina itself. No significant reaction reflecting the presence of amyloid fibril proteins AA, A-lambda, A-kappa, AF(prealb), A-cystatin-C, A-beta-2-microglobulin, A-beta (Congophile angiopathy) occurred in any specimen. It thus seems possible that the fibrils in these deposits are composed of a previously unrecognised amyloid protein.
KeywordsAmyloid Deposit Temporal Artery Amyloid Protein Internal Elastic Lamina Temporal Arteritis
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