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Immunological Examination of Senile Amyloidosis of the Temporal Artery

  • R. P. Linke
  • C. Logan
  • Thos. J. Muckle
  • G. Simon
Chapter

Abstract

Immunohistochemical examination of the amyloid deposits of the internal elastic laminae of temporal arteries taken from aged subjects showed strong reactions reflecting the presence of P-component in relation to the amyloid deposits but not the elastic lamina itself. No significant reaction reflecting the presence of amyloid fibril proteins AA, A-lambda, A-kappa, AF(prealb), A-cystatin-C, A-beta-2-microglobulin, A-beta (Congophile angiopathy) occurred in any specimen. It thus seems possible that the fibrils in these deposits are composed of a previously unrecognised amyloid protein.

Keywords

Amyloid Deposit Temporal Artery Amyloid Protein Internal Elastic Lamina Temporal Arteritis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • R. P. Linke
    • 1
    • 2
  • C. Logan
    • 1
    • 2
  • Thos. J. Muckle
    • 1
    • 2
  • G. Simon
    • 1
    • 2
  1. 1.Department of PathologyMcMaster UniversityCanada
  2. 2.Department of Laboratory MedicineChedoke-McMaster HospitalsHamiltonCanada

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