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Characterization of a Prealbumin Variant in Familial Amyloid Cardiomyopathy of Danish Origin

  • Marianne Nordlie
  • Knut Sletten
  • Gunnar Husby
  • Poul Jørgen Ranløv
Chapter

Abstract

A C-terminal fragment of a prealbumin variant was isolated from amyloid material obtained from the myocardium of a patient (Han) with familial amyloid cardiomyopathy of Danish origin. The prealbumin variant fragment was shown to have a methionine for leucine substitution in position 111.

Keywords

Amyloid Fibril Reversed Phase Chromatography Cyanogen Bromide Partial Amino Acid Sequence Familial Amyloid Polyneuropathy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Marianne Nordlie
    • 1
  • Knut Sletten
    • 1
  • Gunnar Husby
    • 2
  • Poul Jørgen Ranløv
    • 3
  1. 1.Department of BiochemistryUniversity of OsloNorway
  2. 2.Department of RheumatologyUniversity Hospital of TromsøNorway
  3. 3.Department of Medicine BCentral HospitalHillerødDenmark

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