Intracellular Pathways; Exocytic and Endocytic Routes Relying upon Selective Vesicular Transport

  • Colin R. Hopkins
Part of the NATO ASI Series book series (NSSA, volume 218)


For hydrophilic macromolecules to be transported into cells and across tissue barriers the major permeability barriers are the lipid bilayers of the continuous membrane boundaries which surround and compartmentalise all eukaryotic cells. Specialised mechanisms within these boundaries can translocate relatively large molecular species such as polypeptides across the hydrophobic internum of the bilayer but these mechanisms provide major routes of access only into biosynthetic compartments such as the rough endoplasmic reticulum (RER).


Secretory Granule Cytoplasmic Domain Rough Endoplasmic Reticulum Transferrin Receptor Late Endosome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Colin R. Hopkins
    • 1
  1. 1.Department of BiochemistryImperial CollegeSouth Kensington, LondonUK

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