Human Nasal Epithelial Cultures
The proximal airway epithelia act in a coordinated manner to defend the lung from the effects of inhaled foreign materials. The defense mechanisms provided by these airway epithelia are usually analyzed within the framework of the mucociliary clearance system. Nasal epithelia are similar to those of the proximal intrapulmonary airways as both surfaces are populated by relatively equal numbers of ciliated, secretory, and basal cells. The motive force required to move materials trapped in airway surface liquids (ASL) to the oropharynx is provided by the cilia of the ciliated cell.
KeywordsCystic Fibrosis Cholera Toxin Airway Epithelium Tissue Culture Plastic Nasal Epithelium
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