Initial Interactions Between Plant Cells and Agrobacterium Tumefaciens in Crown Gall Tumor Formation

  • Gerard A. Cangelosi
  • Eugene W. Nester
Part of the Recent Advances in Phytochemistry book series (RAPT, volume 22)


Crown gall tumors on dicotyledonous plants are formed by infection of wounded tissue with the bacterial plant pathogen Agrobacterium tumefaciens. Infection of the plant cells does not occur by the bacterial cells themselves, but by a discreet portion of a bacterial, tumor-inducing (Ti) plasmid (Fig. 1). This segment of DNA, termed T-DNA, is found integrated into the nuclear DNA of cloned plant tumor tissue.1,2,3 Expression of T-DNA genes alters the hormone balance of the plant cells,4,5,6 resulting in the tumor phenotype. T-DNA gene products also direct the transformed plant cells to produce opines, unusual amino acids which are utilized by the Agrobacteria.7


Plant Cell Plant Cell Wall Agrobacterium Tumefaciens Crown Gall Pinto Bean 


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Gerard A. Cangelosi
    • 1
  • Eugene W. Nester
    • 1
  1. 1.Department of MicrobiologyUniversity of WashingtonSeattleUSA

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