The Possible Role of Viral Variants in Pathogenesis

  • Charles J. Gauntt
Part of the Infectious Agents and Pathogenesis book series (IAPA)

Abstract

Many different kinds of coxsackievirus (CV) variants have been described and studied with the goal of trying to relate a set of characteristics of a given variant to its pathogenicity in cell cultures or in animal models. In reading about studies about a particular variant, one must remember that any virus stock represents a genotypically heterogeneous population from which phenotypic expression of a dominant variant(s) is observed and measured. Murine models of CV diseases offer exciting possibilities for determining the molecular basis of virulence in these viruses.

Keywords

Attenuation Recombination Influenza Serine Explosive 

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Charles J. Gauntt
    • 1
  1. 1.Department of MicrobiologyThe University of Texas Health Science Center at San AntonioSan AntonioUSA

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