Human T-Cell Responses to Grass Pollen Allergens

  • Sergio Romagnani
  • Shyam S. Mohapatra


Grass pollen allergens constitute a unique class of inhaled antigens that are immunogenic in extremely low doses and are responsible for a number of seasonal allergies, including rhinitis, conjunctivitis, and extrinsic asthma. Grass pollen antigens, as well as other environmental allergens, interact with IgE antibodies specifically and bind to high affinity Fcε receptors (FcεRI) localized on the surface of tissue mast cells and circulating basophils. In response to allergen cross-linkage of their FcεRI, these cells produce and release several potent mediators responsible for allergic symptomatology.


Grass Pollen Grass Pollen Allergen Grass Allergen Grass Pollen Extract Normal Airway Epithelium 
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© Chapman & Hall 1996

Authors and Affiliations

  • Sergio Romagnani
  • Shyam S. Mohapatra

There are no affiliations available

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