Developments in HPLC-MS Interfacing
The benefits to be deduced from on-line operating of high performance liquid chromatography (HPLC, LC) and mass spectrometry (MS) have been recognized for at least 10 years. Both techniques have been developed to extremely powerful tools for the characterization of organic compounds. Unfortunatly, the problem with accomplishing dedicated interfaces are substantial and have proven to be a more challenging task than it had been for gas chromatography mass spectrometry (GC-MS).
KeywordsHigh Molecular Weight Compound Aqueous Solvent Fast Atom Bombardment Mass Spectrometry Sample Molecule Laser Desorption Mass Spectrometry
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