Protein Crystallography

  • David I. Stuart
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 135)


It is over 50 years since the first X-ray photographs of a protein crystal were taken (Bernal & Crowfoot, 1934). Many years were to pass before it was possible to utilize the information inherent in these beautiful diffraction patterns to obtain detailed images of the crystalline proteins.


Protein Crystal High Resolution Data Phase Problem Linear Inverse Relationship Protein Crystallography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Arnold, E. and Rossman, M.G., 1986, Proc. Natl. Acad. Sci. USA, 83:5489.PubMedCrossRefGoogle Scholar
  2. Bernal, J.D. and Crowfoot, D.C., 1934, Nature, 133:794.CrossRefGoogle Scholar
  3. Blundell, T.L. and Johnson, L.N., 1976, “Protein Crystallography”, Academic Press, London.Google Scholar
  4. Bricogne, G., 1984, Acta Cryst., A40:410.Google Scholar
  5. Diesenhofer, J., Michel, H. and Ruber, R., 1985, Trends Biochem. Sci., 10:243.CrossRefGoogle Scholar
  6. Dodson, G., 1986, Trends Biochem. Sci., 11:309.CrossRefGoogle Scholar
  7. Hajdu, J., Acharya, K.R., Stuart, D.I., McLaughlin, P.J., Barford, D., Oikonomakos, N.G., Klein, H. and Johnson, L.N., 1987, EMBO Journal, 6:539.PubMedGoogle Scholar
  8. Hendrickson, W.A., 1985, ‘Methods in Enzymology’, C.H.W. Hirs and S.N. Timasheff eds.. Academic Press, New York, 115:252.Google Scholar
  9. Hendrickson, W.A. and Teeter, M.M., 1981, Nature, 257:107.CrossRefGoogle Scholar
  10. Johnson, L.N., 1985, ‘Modern Physical Methods in Biochemistry, Part A’, Neuberger and Van Deenen Eds, Elsevier, Amsterdam.Google Scholar
  11. Jones, T.A. and Thirup, S., 1986, EMBO Journal, 5:819.PubMedGoogle Scholar
  12. Kahn, R., Fourme, R., Bosshard, R., Weng, J.P., Dideberg, O., Risler, J.L., Brunie, S. and Janin, J., 1984, ‘Structural Biology’, Bartunik and Chance Eds., Academic Press, London.Google Scholar
  13. Lipson, H., and Cochran, W., ‘The Determination of Crystal Structures’, Bell, London.Google Scholar
  14. Phillips, J.C. and Hodgson, K.O., 1980, Acta Cryst., A36:856.Google Scholar
  15. Rossmann, M.G., Arnold, E., Erickson, J.W., Frankenberger, E.A., Griffiths, Hecht, H-J., Johnson, J.E., Kamer, G., Luo, M., Mosser, A.G., Rueckert, R.R., Sherry, B. and Vriend, G. 1985, Nature, 317:145.PubMedCrossRefGoogle Scholar
  16. Samraoui, B., Sutton, B.J., Todd, R.J., Artsrmiuk, P.J., Waley, S.G. and Phillips, D.C., 1986, Nature 320:378.PubMedCrossRefGoogle Scholar
  17. Stuart, D.I., Acharya, K.R., Walker, N.P.C., Smith, S.G., Lewis, M. and Phillips, D.C., 1986a, Nature, 324:84.PubMedCrossRefGoogle Scholar
  18. Stuart, D., Liang, D-C., Dai, J-B., Todd, R., Lou, M-Z., You, J-M., Li, J-Y., and Wang, J-H., 1986b, ‘Structural Biological Applications of X-ray Absorption, Scattering and Diffraction’ Bartunik and Chance Eds., Academic Press, London.Google Scholar
  19. Stuart, D.I. and Phillips, D.C., 1985, in ‘Methods in Enzymology’ C.H.W. Hirs and S.N. Timasheff eds. Academic Press, New York, 115:117.Google Scholar
  20. Sussman, J.L., 1985, in ‘Methods in Enzymology’, C.H.W. Hirs and S.N. Timasheff eds. Academic Press, New York, 271:303.Google Scholar
  21. Wang, B-C., 1985, in ‘Methods in Enzymology’, C.H.W. Hirs and S.N. Timasheff eds.. Academic Press, New York, 90:112.Google Scholar
  22. Wilson, K.S., Stura, E.A., Wild, D.L., Todd, R.J., Stuart, D.I., Babu, Y.S., Jenkins, J.A., Standing, T.S., Johnson, L.N., Forume, R., Kahn, R., Gadet, A., Bartels, K.S., and Bartunik, H.D., 1983, J. Appl. Cryst., 16:28.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • David I. Stuart
    • 1
  1. 1.Laboratory of Molecular BiophysicsUniversity of OxfordOxfordUK

Personalised recommendations