Myosin Light Chain Kinase
Myosin light chain kinase is a widely distributed enzyme found in most tissues in which the actomyosin contractile system is present, the largest amounts occuring in skeletal and smooth muscles. To date the only muscle tissue in which the enzyme has been sought and not detected is molluscan adductor (Frearson et al., 1976). The natural substrate for the enzyme is the phosphorylatable (P) light chain in the intact myosin molecule (Fig. 1). This light chain has a Mr of 18000–20000 and is also known as light chain 2 (LC2), the dithiobisnitrobenzoic acid (DTNB) or regulatory light chain.
KeywordsLight Chain Myosin Light Chain Kinase Myosin Head Smooth Muscle Myosin Rabbit Skeletal Muscle
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