Myosin Light Chain Kinase

  • S. V. Perry
Conference paper
Part of the NATO ASI Series book series (NSSA, volume 135)


Myosin light chain kinase is a widely distributed enzyme found in most tissues in which the actomyosin contractile system is present, the largest amounts occuring in skeletal and smooth muscles. To date the only muscle tissue in which the enzyme has been sought and not detected is molluscan adductor (Frearson et al., 1976). The natural substrate for the enzyme is the phosphorylatable (P) light chain in the intact myosin molecule (Fig. 1). This light chain has a Mr of 18000–20000 and is also known as light chain 2 (LC2), the dithiobisnitrobenzoic acid (DTNB) or regulatory light chain.


Light Chain Myosin Light Chain Kinase Myosin Head Smooth Muscle Myosin Rabbit Skeletal Muscle 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • S. V. Perry
    • 1
  1. 1.Department of Physiology Medical SchoolUniversity of BirminghamBirminghamUK

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