Protein Phosphorylation: A Historical Overview

  • Edmond H. Fischer
Part of the NATO ASI Series book series (NSSA, volume 135)


This first lecture will offer a rapid overview of one of the most prevalent mechanisms organisms have devised to regulate their cellular function, that is, phosphorylation-dephosphorylation of proteins.


Carbohydrate Metabolism Protein Phosphorylation Pyruvate Dehydrogenase Covalent Modification Myosin Light Chain Kinase 
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  1. Fischer, E.H., Brautigan, D.L., (1982) TIBS, Vol. 7, No. 1, 0. 3–4Google Scholar
  2. Fischer, E.H., (1983) Bulletin de L’Institut Pasteur 81, p. 7–31.Google Scholar
  3. Krebs, E.G., (1981) Cukrr, topics in Cell. Reg., 18, 401–419.Google Scholar
  4. Cohen, P. (1982) Nature 296, 613–620.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Edmond H. Fischer
    • 1
  1. 1.Department of BiochemistryUniversity of WashingtonSeattleUSA

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