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An Approach to Automated Cytotoxicity Testing by Means of Digital Image Processing

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Real-Time Medical Image Processing

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Abstract

HLA antigens exist on the surface of human lymphocytes and have been widely investigated as histocompatibility antigens mainly in connection with kidney transplantation. In addition to this, it has recently been found that there are associations between certain types of HLA antigens and various diseases. The microdroplet lymphocytotoxicity test is universally accepted as the standard method for HLA antigen determination (Terasaki et al., 1978).

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References

  • Bruning, J. W., Douglas, R., Scholtus, M., and van Rood, J. J., “Automatic Reading and Recording of the Microlymphocytotoxicity Test,” Tissue Antigens 2:473–477 (1972).

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  • Taylor, W. K., “An Automatic System for Obtaining Particle Size Distribution with the Aid of the Flying Spot Microscope,” Brit. J. Appl. Phys. Suppl. 3:173–175 (1954).

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  • Terasaki, P. I., Bernoco, D., Park, M. S., Ozturk, G., and Iwaki, Y., “Microdroplet Testing for HLA-A,-B,-C, and-D Antigens,” Am. J. Clin. Path. 69: 103–120 (1978).

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  • Wilson, M., Dardano, J., and Rothschild, H., “An Automated, Rapid, and Quantitative Microassay for Histocompatibility Testing,” Transplantation 16(5): 408–414 (1973).

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Author information

Authors and Affiliations

  1. Research Laboratory, Nippon Kogaku K.K., Nishioi, Tokyo, Japan

    A. Kawahara

Authors
  1. A. Kawahara
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Editor information

Editors and Affiliations

  1. University of Tokyo, Tokyo, Japan

    Morio Onoe

  2. Carnegie-Mellon University, Pittsburgh, Pennsylvania, USA

    Kendall Preston Jr.

  3. University of Maryland, College Park, Maryland, USA

    Azriel Rosenfeld

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© 1980 Plenum Press, New York

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Kawahara, A. (1980). An Approach to Automated Cytotoxicity Testing by Means of Digital Image Processing. In: Onoe, M., Preston, K., Rosenfeld, A. (eds) Real-Time Medical Image Processing. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0121-0_12

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  • DOI: https://doi.org/10.1007/978-1-4757-0121-0_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0123-4

  • Online ISBN: 978-1-4757-0121-0

  • eBook Packages: Springer Book Archive

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