Enzymology of Indole Alkaloid Biosynthesis

  • K. M. Madyastha
  • Carmine J. Coscia
Part of the Recent Advances in Phytochemistry book series (RAPT, volume 13)


The monoterpenoid indole alkaloids are a large family of structurally diverse compounds encompassing some of the most important plant medicinais discovered by man. Although these alkaloids were one of the last major groups of well-known natural products to have their biogenesis delineated, they have become one of the first classes of plant secondary metabolites to be studied at the enzymatic level. A contributory factor has been the excellent progress made by in vivo tracer work, which within a little more than a decade has led to the elucidation of the major features of a highly complicated pathway1,2.


Hydroxylase Activity Heme Protein Indole Alkaloid Papaver Somniferum Alkaloid Biosynthesis 
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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • K. M. Madyastha
    • 1
  • Carmine J. Coscia
    • 1
  1. 1.E. A. Doisy Department of BiochemistrySaint Louis University School of MedicineSt. LouisUSA

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