Sphingolipids are widely distributed in nature, yet their biological function(s) is not well understood. However, certain groups of these lipids exhibit immunological activity and they are constituents of cellular membranes. High amounts of sphingolipids are associated with nerve tissue. Considerable interest in these lipids developed because they are associated with certain diseases called lipidoses (sphingolipidoses). These diseases result from inborn errors in sphingolipid metabolism; the absence or low activity of certain degradative enzymes resulting in the accumulation of specific sphingolipids in certain tissues.
KeywordsAgaricus Bisporus Sphingolipid Metabolism Chain Base Principal Fatty Acid Complex Sphingolipids
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