Elastosis in Human Breast Cancer. Part II. Biochemical Studies
It is known since several decades that in many cases of infiltrating epitheliomas of human breast variable amounts of elastic fibers may appear. This finding was reported and studied mainly by anatomo-pathologists using morphological techniques (see Part I of this report for the bibliography by Adnet et al., this volume). The main problems which have been discussed concerned the identity of these fibers with elastic fibers seen in other parts of the organism and the possible diagnostic or prognostic importance of this breast cancer elastosis. In our knowledge however no detailed chemical investigation was undertaken on this interesting and important subject. We started such an investigation a few years ago and the purpose of this chapter is to summarize the results we obtained and which were shortly reported (Hornebeck and Robert, 1977; Hornebeck et al., 1977, 1978).
KeywordsBreast Cancer Human Breast Cancer Elastic Fiber Elastin Content Matrix Biology
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