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Tumor Associated Markers in Breast Cancer

  • P. Franchimont
  • P. F. Zangerle
  • J. Collette
  • C. Colin
  • P. Osterrieth
  • J. C. Hendrick
  • J. R. Van Cauwenberge
  • J. Hustin

Abstract

Several tumor markers have been assayed in serum of patients suffering from breast diseases in order to improve the early detection of cancer, to contribute to its diagnosis, to evaluate the local and metastatic extension of the neoplasia, to monitor the follow-up of previously diagnosed cancer and to provide useful prognosis information. In this article, the potential interest of some tumor markers will be stressed as the limits of some others.

Keywords

Breast Cancer Tumor Marker Carcino Embryonic Antigen Breast Disease Breast Cyst 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Black, M.M., Zachrau, R.E., Dion, A.S., Shore, B., Fine, D.L., Leis, H.P. Jr., and Williams, C.J., 1976, Cellular hypersensitivity to GP55 of RIII Murine Mammary Tumor Virus and GP55-like protein of human breast cancers. Cancer Res., 36, 4137–4142.PubMedGoogle Scholar
  2. Colin, C., Submitted for publication (1979).Google Scholar
  3. Day, N.K., 1979, Communication at the XXVII Annual Colloquium on: “Protides of the biological fluids”, Brussels.Google Scholar
  4. Franchimont, P., Debruche, M.L., Zangerle, P.F., and Proyard, J., 1974, Carcinoembryonic antigen (CEA). In: “Radioimmunoassay and Related Procedures in Medicine”, Vol. II, International Atomic Energy Agency, Vienne, 267–274.Google Scholar
  5. Franchimont, P., Zangerle, P.F., Debruche, M.L., Proyard, J., Simon, P., and Gaspard, U., 1975, Dosage radioimmunologique de l’alpha foeto proteine dans les différentes conditions normales et pathologiques. Ann. Biol. Clin., 33, 139–148.Google Scholar
  6. Franchimont, P., Zangerle, P.F., Nogarede, J., Bury, J., Molter, F., Reuter, A., Hendrick, J.C., and Collette, J., 1976, Simultaneous assays of cancer-associated antigens in various neoplastic disorders. Cancer, 38, 2287–2295.PubMedCrossRefGoogle Scholar
  7. Franchimont, P., Zangerle, P.F., Hendrick, J.C., Reuter, A., and Colin, C., 1977, Simultaneous assays of cancer associated antigens in benign and malignant breast diseases. Cancer, 39, 2806–2812.PubMedCrossRefGoogle Scholar
  8. Franchimont, P., Reuter, A., and Gaspard, U., 1978, Ectopic production of human chorionic gonadotropin and its α-and β-subunits. In: “Current Topics in Experimental Endocrinology”, L. Martini and V.H.T. James, Eds., Academic Press, New York, London, Vol. 3, 204–216.Google Scholar
  9. Franchimont, P., Hendrick, J.C., Thirion, A., and Zangerle, P.F., 1979, Kappa casein: an index of normal mammary function and tumor associated antigen. In: “Immunodiagnosis of Cancer”, R.B. Herberman and K.R. McIntire, Eds., M. Dekker, Inc., New York, Basel, Part I, 499–512.Google Scholar
  10. Furmanski, P., Loeckner, C.P., Longley, C., Larson, L.J., and Rick, M.A., 1976, Identification and isolation of the major core protein from the oncornavirus-like particle in human milk. Cancer Res., 36, 4001–4007.PubMedGoogle Scholar
  11. Kaagensen, D.E. Jr., Mazoujian, G., Holder, W. Jr., Kister, S.J., and Wells, S.A. Jr., 1976, Evaluation of a breast cyst fluid protein detectable in the plasma of breast carcinoma patients. Ann. Surg., 3, 277–289.Google Scholar
  12. Hendrick, J.C., Thirion, A., and Franchimont, P., 1976, Radioimmunoassay of casein. In: “Cancer Related Antigens”, P. Franchimont, Ed., North-Holland, Amsterdam, 51–59.Google Scholar
  13. Hendrick, J.C., François, C., Calberg-Bacq, C.M., Colin, C., Franchimont, P., Gosselin, L., Kozma, S., and Osterrieth, P.M., 1978, Radioimmunoassay for protein p28 of murine mammary tumor virus in organs and serum of mice and search for related antigens in human sera and breast cancer extracts. Cancer Res., 38, 1826–1830.PubMedGoogle Scholar
  14. Heynen, G., 1976, Discussion in “Cancer Related Antigens“, P. Franchimont, Ed., North-Holland, Amsterdam, New York, 160–162.Google Scholar
  15. Loisillier, F., Saracino, J., Metivier, D., and Burtin, P., 1979, Characterisation of an antigen associated to human mammary carcinoma. In: “Protides of the biological fluids”, XXVII Annual Colloquium, Brussels, Abstr. n° 65.Google Scholar
  16. Muller, M., Zotter, S., and Kemmer, C., 1976, Specificity of human antibodies to intracytoplasmic type A particles of the murine mammary tumor virus. J. Natl. Cancer Inst., 56, 295–303.PubMedGoogle Scholar
  17. Zangerle, P.F., Calberg-Bacq, C.M., Colin, C., Franchimont, P., François, C., Gosselin, L., Kozma, S., and Osterrieth, P.M., 1977, Radioimmunoassay for glycoprotein GP47 of murine mammary tumor virus in organs and serum of mice and search for related antigens in human sera. Cancer Res., 37, 4326–4331.Google Scholar
  18. Zangerle, P.F., Collette, J., and Franchimont, P., 1979, Specific radioimmunoassay for gross cystic disease fluid protein (G.C.D.F.P.). Submitted for publication.Google Scholar

Copyright information

© Plenum Press, New York 1981

Authors and Affiliations

  • P. Franchimont
    • 1
  • P. F. Zangerle
    • 1
  • J. Collette
    • 1
  • C. Colin
    • 2
  • P. Osterrieth
    • 3
  • J. C. Hendrick
    • 1
  • J. R. Van Cauwenberge
    • 2
  • J. Hustin
    • 2
  1. 1.Institute of Medicine, Radioimmunoassay LaboratoryUniversity of LiègeBelgium
  2. 2.Obstetrics and Gynecology DepartmentUniversity of LiègeBelgium
  3. 3.Bacteriology and Virology DepartmentUniversity of LiègeBelgium

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