Role of Local [Ca+2] in the Control of Cell Function

  • Fredric S. Fay
  • David A. Williams
  • Gary Kargacin
  • Robert W. Tucker
  • Mary Scanlon
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 232)


Ca+2 is believed to play an essential role in the regulation of cell function. While this has been suspected for many years, the inability to directly measure [Ca+2] in small cells of physiological interest precluded obtaining definitive insights into many aspects of this process. We have been interested in the mechanisms underlying the generation and regulation of force in smooth muscle and thus for many years, have been interested in the role of Ca+2 in this process.


Smooth Muscle Cell Sarcoplasmic Reticulum Contractile Response Calcium Transient Calcium Chelator 


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Fredric S. Fay
    • 1
  • David A. Williams
    • 1
  • Gary Kargacin
    • 1
  • Robert W. Tucker
    • 1
    • 2
  • Mary Scanlon
    • 1
  1. 1.Dept. of PhysiologyUniversity of Massachusetts Medical SchoolNorth WorcesterUSA
  2. 2.Oncology CenterJohns Hopkins University School of MedicineBaltimoreUSA

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