Metalloproteins in Developing Artemia
There is an increasing awareness of the importance of essential trace metals, particularly zinc and copper, in normal cell growth and development . Central to this theme has been the postulated direct involvement of zinc in the control of gene expression . A number of zinc metalloproteins have been reported to be involved in replication and transcription, including RNA and DNA polymerases . Thus, the question arises as to the mechanism by which the activity of these enzymes might be directly regulated by cytosolic trace metals.
KeywordsMetal Binding Zinc Level High Molecular Weight Protein Essential Trace Metal Cadmium Binding
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- 4.J. S. Hanas, D. J. Hazuda, D. R. Bogenhagen, F. Y.-H. Wu and C.-W. Wu, Xenopus transcription factor A requires a zinc for binding to the 5s RNA gene, Biol. Chem. 258:14120 (1983).Google Scholar
- 14.M. Karin, M. Imagawa, R. J. Imbra, R. Chiu, A. Heguy, A. Haslinger, T. Cooke, S. Satabhama, C. Jonat and P. Herrlich, Hormonal and environmental control of metallothionein gene expression, in: “Transcriptional Control Mechanisms,” 1D. Granner, G. Rosenfeld, S. Chang, eds., Alan R. Liss, New York (1987).Google Scholar
- 16.K. E. Mayo and R. D. Palmiter, Glucocorticoid regulation of the mouse metallothionein 1 gene is selectively lost following amplification of the gene, J. Biol. Chem. 257:306 (1982).Google Scholar
- 23.A. Thall and R. Acey, Cadmium binding proteins in developing Artemia salina, Fed. Proc. 44:1462 (1985).Google Scholar
- 24.Y. H. Nakanishi, T. Iwasaki, T. Okigaki and H. Kato, Cytological studies of Artemia salina. Embryonic development without cell multiplication after the blastula in encysted dry eggs, Annot. Zool. Japon. 35:223 (1962).Google Scholar
- 25.J. C. Bagshaw and R. Acey, Stage-specific gene expression in Artemia in: “Biochemistry of Artemia Development,” J. C. Bagshaw and A. H. Warner, eds., University Microfilms International, Ann Arbor (1979).Google Scholar
- 28.K. Suzuki, Y. Ebihara, H. Akitomi, M. Nishikawa and R. Kawamura, Change in ratio of the two hepatic isometallothioneins with develoment from prenatal to neonatal rats, Comp. Biochem. Physiol. 76C: 33 (1983).Google Scholar
- 29.D. G. Wilkerson and M. Nemer, Metallothionein genes MTa and MTb expressed under distinct quantitative and tissue specific regulation in sea urchin embryos, Mol. Cellular Biol. 7:48 (1987).Google Scholar
- 31.R. Acey, Induction of a zinc binding protein during the early embryonic development of the brine shrimp Artemia salina, J. Cell. Biochem. Supplement D:354 (1988).Google Scholar
- 34.A. Cano, J. Crucus, I. Estepa, M. E. Gallego, M. A. G. Sillero, C. F. Heredia, P. Liorente, A. Olalla, C. Osuna, A. Pestana, J. Renart, A. Ruiz, L. Sastre, J. Sebastian and A. Sillero, Developmental changes of enzyme levels during Artemia salina differentiation, in: “Biochemistry of Artemia Development,” J. C. Bagshaw and A. H. Warner, eds., University Microfilms International, Ann Arbor (1979).Google Scholar
- 37.C. G. Vallejo, F. de Luchi, J. Laynez and R. Marco, The role of cytochrome oxidase in the resumption of the development of Artemia dormant cysts, in: “The Brine Shrimp Artemia,” G. Persoone, P. Sorgeloos, O. Roels and E. Jaspers, eds., Universa Press, Wettren (1980).Google Scholar