Abstract
Over the last 30 years, transition-state theory has provided a suitable theoretical framework for interpreting a wide range of chemical(1) and biological(2) processes. Nevertheless, it is only within the last few years, due in large measure to the approximately parallel and related development of high-speed digital computers and practical quantum-mechanical procedures for studying the geometric and electronic structure of molecules, that the full potential of transition-state theory is beginning to be realized.
Keywords
- Transition State
- Potential Energy Surface
- Reaction Path
- Potential Energy Function
- Kinetic Isotope Effect
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Maggiora, G.M., Christoffersen, R.E. (1978). Quantum-Mechanical Approaches to the Study of Enzymic Transition States and Reaction Paths. In: Gandour, R.D., Schowen, R.L. (eds) Transition States of Biochemical Processes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-9978-0_3
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