Regulation of Oocyte Maturation

  • Nava Dekel
Part of the Biochemical Endocrinology book series (BIOEND)


Meiotic maturation in the mammalian oocyte is initiated during fetal life. It proceeds through the prophase of the first meiotic division and is arrested at the diplotene stage. The arrest of meiosis is maintained until shortly before ovulation. By this time meiosis is reinitiated and oocyte maturation is resumed. Reinitiation of meiosis in the oocyte is morphologically indicated by the disappearance of the nuclear structure known as the germinal vesicle (germinal vesicle breakdown — GVB).


cAMP Level Follicular Fluid Oocyte Maturation Cumulus Cell Mouse Oocyte 
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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • Nava Dekel
    • 1
  1. 1.Department of Hormone ResearchThe Weizmann Institute of ScienceRehovotIsrael

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