Strategies for the Inhibition of Gonadotropin Action

  • M. R. Sairam
Part of the Biochemical Endocrinology book series (BIOEND)


The growth and maintenance of gonadal functions are directly under the control of pituitary gonadotropins. In special events such as pregnancy the placenta also provides important gonadotropic support by secreting highly active choriogonadotropins. In view of this various approaches for curtailing their action have been constantly sought as suitable points of attack to control reproduction. The isolation, characterization and structure of the gonadotropic hormones and the hypothalamic releasing factor LH-RH and the synthesis of numerous analogs of the latter with differing and well defined biological activity have intensified research in this direction.


Follicular Fluid Pituitary Gonadotropin Gonadotropic Hormone Gonadotropin Receptor Testicular Receptor 
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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • M. R. Sairam
    • 1
  1. 1.Reproduction Research LaboratoryClinical Research Institute LaboratoryMontrealCanada

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