The Regulation of Cell Behavior by Cell Adhesion

  • Paul C. Letourneau
  • Peter N. Ray
  • Merton R. Bernfield
Part of the Biological Regulation and Development book series (BRD, volume 2)


The complex morphogenesis of tissues and their successful participation in an organism’s homeostasis depend on regulatory interactions of the tissue cells with their environment. The influence of soluble extrinsic molecules on genetic expression is best illustrated by the powerful effects of hormones. Less well appreciated but also with significant effects on genetic expression are the contacts and physical associations that nearly all cells make with other cells or with extracellular structures. The importance of these associations to cell function is poorly understood, because they are not easily manipulated or assessed in situ, and even when duplicated in vitro one must determine which aspects of cellular contact are regulatory.


Cell Adhesion Cell Shape Growth Cone Basal Lamina Contact Inhibition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1980

Authors and Affiliations

  • Paul C. Letourneau
    • 1
  • Peter N. Ray
    • 2
  • Merton R. Bernfield
    • 3
  1. 1.Department of AnatomyUniversity of MinnesotaMinneapolisUSA
  2. 2.Department of Medical GeneticsUniversity of TorontoTorontoCanada
  3. 3.Department of PediatricsStanford University School of MedicineStanfordUSA

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