Advertisement

Clinical Importance of Detecting Mycoplasma Contamination of Cell Cultures

  • Edward L. Schneider
Part of the Cellular Senescence and Somatic Cell Genetics book series (CSSCG, volume 3)

Abstract

The preceding papers in this symposium have convincingly detailed the wide range of cellular alterations induced by mycoplasma infection. It is also apparent that considerable advances have been achieved in the technology employed for detecting mycoplasma contamination of cells in culture. Therefore, it behooves the investigator working with cultured cells to be certain that he is examining uncontaminated cell cultures. It is also becoming increasingly clear that mycoplasma contamination may represent a hazard to successful clinical use of cell cultures.

Keywords

Prenatal Diagnosis Chromosomal Alteration Mycoplasma Contamination Mycoplasma Infection Amniotic Fluid Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Taylor-Robinson, D. Workshop on Mycoplasma Infection of Cell Cultures, Institute for Medical Research, Camden, New Jersey, March 22-23, 1977. In press.Google Scholar
  2. 2.
    Golbus, M. S. The prenatal diagnosis of genetic defects In Advances in Obstetrics and Gynecology, Williams and Wilkins, Baltimore, 1977.Google Scholar
  3. 3.
    Schneider, E. L., Epstein, C. J., Epstein, W. J., Halbasch, G., and Betlach, M. Exp. Cell Res. 79: 343348, 1973.Google Scholar
  4. 4.
    Schneider, E. L., Stanbridge, E. J., and Epstein, C. J. Exp. Cell Res. 84: 311 - 318, 1974.PubMedCrossRefGoogle Scholar
  5. 5.
    Schneider, E. L., Stanbridge, C. J., Golbus, M., Halbasch, G. and Rodgers, G. Science 184: 477 - 479, 1974.PubMedCrossRefGoogle Scholar
  6. 6.
    Latt, S. A. Science 185: 74 - 76, 1974.Google Scholar
  7. 7.
    Wolff, S. and Perry, P. Chromosoma (Berl) 48: 341 - 353, 1974.CrossRefGoogle Scholar
  8. 8.
    Brown, R. L. and Crossen, P. E. Exp. Cell Res. 103: 418420, 1976.Google Scholar
  9. 9.
    Stanbury, J. B. Wyngaarden, J. B. and Fredrickson, D. S. The Metabolic Basis of Inherited Diseases, 3rd Edit., McGraw-Hill, New York, 1972.Google Scholar
  10. 10.
    Stanbridge, E. J., Tischfield, J. A. and Schneider, E. L. Nature 256: 329 - 331, 1975.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1978

Authors and Affiliations

  • Edward L. Schneider
    • 1
  1. 1.Laboratory of Cellular and Comparative PhysiologyGerontology Research Center, National Institute on Aging, National Institutes of Health, PHS, U. S. Department of Health, Education and WelfareBaltimoreMarylandUK

Personalised recommendations