Abstract
The consequences of inhibitory or excitatory synaptic input between pacemaker neurons were predicted mathematically and through digital-computer simulations, and the predicted behavior was found to occur in abdominal ganglia of Aplysia and in stretch receptors of Procambarus. Discharge patterns under conditions that do not involve interneuronal feedback are characteristic and self-stabilizing. Paradoxically, increased arrival rates of inhibitory input can increase firing rates, and increased excitatory input rates can decrease firing rates.
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Supported in parr by research grants und a research senior r arch fello„shi p (1. P. S.) Iron) NIB, and bv research grams from NSF. We thank S. and D. Fromson and R. Kaplan for technical a.ssistance and 1. Barlow and D. Mohr for help in the computations.
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Perkel, D.H., Schulman, J.H., Bullock, T.H., Moore, G.P., Segundo, J.P. (1993). Pacemaker Neurons: Effects of Regularly Spaced Synaptic Input. In: How do Brains Work?. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4684-9427-3_12
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DOI: https://doi.org/10.1007/978-1-4684-9427-3_12
Publisher Name: Birkhäuser, Boston, MA
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