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Neuroepidemiology of Parkinson’s Disease: Environmental Influences

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Book cover Etiopathogenesis

Part of the book series: Advances in Research on Neurodegeneration ((ARN,volume 2))

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Abstract

Descriptive epidemiology of Parkinson’s disease (PD), by providing a profile of the disease, should be useful in the etiological investigation of PD. Etiological hypotheses need to be consistent with known epidemiologic factors, and descriptive epidemiologic observations may generate a new hypothesis. Analytic epidemiology seeks to identify risk factors that could lead to clues for causal associations with the disease.

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References

  • Aquilonius SM, Hartvig P (1986): A Swedish county with unexpectedly high utilization of anti-parkinsonian drugs. Acta Neurol Scand74:379

    Article  PubMed  CAS  Google Scholar 

  • Ashok PP, Radhakrishnan K, Sridharan R, Mousa ME (1986): Epidemiology of Parkinson’s disease in Benghazi, north-east Libya. Neurosurgery88(2): 109–113

    CAS  Google Scholar 

  • Bademosi O, Al-Rajeh IH, Awada A (1991): Prevalence of Parkinson’s disease (PD) in an Arab community: the Thugbah study. In: Congres de neurologie tropicale, September 26–28, 1991, p. 27. Recherche en Neurologic Tropicale Press

    Google Scholar 

  • Barbeau A, Roy M (1985): Uneven prevalence of Parkinson’s disease in the province of Quebec. Can J Neurol Sci12:169–170

    Google Scholar 

  • Barbeau A, Roy M, Bernier G, et al. (1987): Ecogenetics of Parkinson’s disease: prevalence and environmental aspects in rural areas. Can J Neurol Sci14:36–41

    PubMed  CAS  Google Scholar 

  • Baumann RJ, Jamesson HD, McKean HE, Haack DG, Weisburg LM (1980): Cigarette smoking and Parkinson’s disease. I. A comparison of cases with matched neighbors. Neurology30:839

    Article  PubMed  CAS  Google Scholar 

  • Bharucha NE, Bharucha EP, Bharucha AE, Bhise AV, Schoenberg BS (1988): Prevalence of Parkinson’s disease in the Parsi community in Bombay, India. Arch Neurol45:1321–1323

    Article  PubMed  CAS  Google Scholar 

  • Bodmer WF (1973): Population genetics of the HLA system: retrospect and prospect. In: Histocompatibility Testing 1972, Dausset J, Colombani J, eds., pp. 611–667. Copenhagen: Munksgaard

    Google Scholar 

  • Brewis M, Poskanzer DC, Rolland C, Miller H (1966): Neurological disease in an English city. Acta Neurol Scand42(Suppl 24): 1–89

    PubMed  Google Scholar 

  • Broman T (1963): Parkinson’s syndrome, prevalence and incidence in Goteborg. Acta Neurol Scand51 (Suppl 4):95–101

    Google Scholar 

  • Burch PRJ (1981): Cigarette smoking and Parkinson’s disease. Neurology31:500.

    PubMed  CAS  Google Scholar 

  • Burns SP, Chiueh CC, Markey SP, Ebert MH, Jacobowitz DM, Kopin IJ (1983): A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci USA80:4546–4550

    Article  PubMed  CAS  Google Scholar 

  • Calne DB, Langston JW (1983): Aetiology of Parkinson’s disease. Lancet2:1457–1459

    Article  PubMed  CAS  Google Scholar 

  • Casetta I, Granieri E, Govoni V, et al. (1990): Epidemiology of Parkinson’s disease in Italy. A descriptive survey in the U.S.L. of Cento, province of Ferrara, Emilia-Romagna. Acta Neurol(Napoli) 12:284–291

    CAS  Google Scholar 

  • Clifford WB, Heaton TB, Voss PR, Fuguitt GV (1985): The rural elderly in demographic perspective. In: The Elderly in Rural Society: Every Fourth Elder, Coward RT, Lee GR, eds., pp. 25–55. New York: Springer

    Google Scholar 

  • D’Alessandro R, Gamberini G, Granieri E, Benassi G, Naccarato S, Manzaroli D (1987): Prevalence of Parkinson’s disease in the Republic of San Marino. Neurology37:1679–1682

    Article  PubMed  Google Scholar 

  • Dupont E (1977): Epidemiology of parkinsonism. The Parkinson investigation, Arhus, Denmark (preliminary results). In: Symposium on Parkinsonism, Worm-Peterson J, Bottcher J, eds., pp. 65–75. Denmark: Merck, Sharp & Dohme

    Google Scholar 

  • Golbe LI, Farrell T (1988): Case-control survey of early-adult dietary habits in Parkinson’s disease. Neurology38(Suppl 1):204

    Google Scholar 

  • Granieri E, Carreras M, Casetta I, et al. (1991): Parkinson’s disease in Ferrara, Italy, 1967 through 1987. Arch Neurol48:854–857

    Article  PubMed  CAS  Google Scholar 

  • Gudmundsson KR (1967): A clinical survey of parkinsonism in Iceland. Acta Neurol Scand43(Suppl) 33:1–61

    Google Scholar 

  • Harado H, Nishikawa S, Takahashi K (1983): Epidemiology of Parkinson’s disease in a Japanese city. Arch Neurol40:151–154

    Article  Google Scholar 

  • Ho SC, Woo J, See CM (1989): Epidemiologic study of Parkinson’s disease in Hong Kong. Neurology39:1314–1318

    Article  PubMed  CAS  Google Scholar 

  • Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992): The accuracy of the clinical diagnosis of Parkinson’s disease: a clinicopathological study of 100 cases. J Neurol Neurosurg Psychiatry55:181–184

    Article  PubMed  CAS  Google Scholar 

  • Jannson B, Jankovic J (1985): Low cancer rates among patients with Parkinson’s disease. Ann Neurol17:505

    Article  Google Scholar 

  • Jenkins AC (1966): Epidemiology of parkinsonism in Victoria. Med J Aust2:496–502

    PubMed  CAS  Google Scholar 

  • Jenner P, Marsden CD (1988): MPTP-induced parkinsonism in primates and its use in the assessment of novel strategies for the treatment of Parkinson’s disease. In: Current Problems in Neurology (6): Parkinson’s Disease: Clinical and Experimental Advances, Rose FC, ed., pp. 149–162. London: John Libbey

    Google Scholar 

  • Jimenez-Jimenez FJ, Gonzales DM, Gimrnez-Roldan S (1988): Exposure to well water drinking and pesticides in Parkinson’s disease. In: Proceedings of the Ninth International Symposium on Parkinson’s Disease, p. 118, World Congress of Neurology, Jerusalem

    Google Scholar 

  • Kessler II (1972): Epidemiologic studies of Parkinson’s disease. A hospital-based survey. Am J Epidemiol95:308–318

    PubMed  CAS  Google Scholar 

  • Kessler II (1973): Parkinson’s disease: perspectives on epidemiology and pathogenesis. Prev Med2:88–105

    Article  PubMed  CAS  Google Scholar 

  • Koller WC (1983): Alcoholism in essential tremor. Neurology33:1074

    Article  PubMed  CAS  Google Scholar 

  • Koller WC (1992): When does Parkinson’s disease begin? Neurology43(Suppl 4):27–31

    Google Scholar 

  • Koller WC, Vetere-Overfield B, Gray C, Alexander C, Chin T, Dolezal, Hassanein R, Tanner C (1990): Environmental risk factors in Parkinson’s disease. Neurology40: 1218–1221

    Article  PubMed  CAS  Google Scholar 

  • Kurland LT (1958): Epidemiology: incidence, geographic distribution and genetic considerations. In: Pathogenesis and Treatment of Parkinsonism, Field WS, ed., pp. 5–49. Springfield, IL: Charles C. Thomas

    Google Scholar 

  • Kurtzke JF, Murphy FM (1990): The changing patterns of death rates in parkinsonism. Neurology40:42–49

    Article  PubMed  CAS  Google Scholar 

  • Langston JW, Langston EB, Irwin I (1984a): MPTP-induced parkinsonism in human and non-human primates. Clinical and experimental aspects. Acta Neurol Scand70:49–54

    Google Scholar 

  • Langston JW, Forno LS, Rebert CS, Irwin (1984b): Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the squirrel monkey. Brain Res292:390–394

    Article  PubMed  CAS  Google Scholar 

  • Li SC, Schoenberg BS, Wang CC, et al. (1985): A prevalence survey of Parkinson’s disease and other movement disorders in the People’s Republic of China. Arch Neurol42:655–657

    Article  PubMed  CAS  Google Scholar 

  • Marmot M (1981): Mortality and Parkinson’s disease. In: Research Progress in Parkinson’s Disease 1980, Rose F, Capildeo R, eds. pp. 9–16. Kent: Tunbridge Wells

    Google Scholar 

  • Marttila RJ, Rinne U (1976): Epidemiology of Parkinson’s disease in Finland. Acta Neurol Scand53:81–102

    Article  PubMed  CAS  Google Scholar 

  • Meador KJ, Meador MP, Loring DS, et al. (1987): Neuroepidemiology of Parkinson’s disease. Neurology37(Suppl 1): 120

    Google Scholar 

  • Mitchell IJ, Cross AJ, Sambrook MA, Crossman AR (1985): Sites of the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the macaque monkey include the ventral tegmental area and the locus coeruleus. Neurosci Lett61:195–200

    Article  PubMed  CAS  Google Scholar 

  • Morgante L, Racco WA, Rosa AE (1992): Prevalence of Parkinson’s disease and other types of parkinsonism: a door-to-door survey in three Sicilian municipalities. Neurology42: 1901–1906

    Article  PubMed  CAS  Google Scholar 

  • Nobrega FT, Glattre E, Kurland LT, Okazaki H (1969): Comments on the epidemiology of parkinsonism including prevalence and incidence statistics for Rochester, Minnesota, 1935–1936. In: Progress in Neuro-Genetics: Proceedings of the International Congress of Neuro-Genetics, Barbeau A, Brunette JS, eds., pp. 474–485. Amsterdam: Excerpta Medica

    Google Scholar 

  • Okada K, Kobayashi S, Tsunematsu T (1990): Prevalence of Parkinson’s disease in Izumo City, Japan. Gerontology36:340–344

    Article  PubMed  CAS  Google Scholar 

  • Rajput AH, Stern W, Christ A, Laverty W (1984a): Etiology of Parkinson’s disease: environmental factor(s). Neurology34(Suppl 1):207

    Google Scholar 

  • Rajput AH, Offurd KP, Beard CM, Kurland LT (1984b): Epidemiology of parkinsonism: incidence, classification, and mortality. Ann Neurol16:278–282

    Article  PubMed  CAS  Google Scholar 

  • Rajput AH, Offurd KP, Beard CM, Kurland LT (1984c): A case-control study of smoking habits, dementia, and other illnesses in idiopathic Parkinson’s disease. Neurology37:226

    Article  Google Scholar 

  • Rajput AH, Uitti RJ, Stern W, et al. (1987b): Geography, drinking water chemistry, pesticides, and herbicides and the etiology of Parkinson’s disease. Can J Neurol Sci14:414

    PubMed  CAS  Google Scholar 

  • Rajput AH, Uitti RJ, Stern W, et al. (1986): Early onset Parkinson’s disease in Saskatchewan: environmental considerations for etiology. Can J Neurol Sci13:212–216

    Google Scholar 

  • Rosati G, Granieri E, Pinna L, et al. (1978): Parkinson’s disease. Prevalence and incidence in the province of Sassari, North Sardinia. Acta Neurol(Napoli) 33:210–207

    Google Scholar 

  • Rosati G, Granieri E, Pinna L, Devoto MC (1979): The frequency of Parkinson’s disease in the province of Nuoro (Sardinia). Acta Neurol1:303–308

    CAS  Google Scholar 

  • Rosati G, Granieri E, Pinna L, et al. (1980): The risk of Parkinson’s disease in Mediterranean people. Neurology30:250–255

    Article  PubMed  CAS  Google Scholar 

  • Sasco AJ, Paffenberger RS, Jr (1985): Measles infection and Parkinson’s disease. Am J Epidemiol122:1017

    PubMed  CAS  Google Scholar 

  • Schoenberg BS, Anderson DW, Haerer AF (1985): Prevalence of Parkinson’s disease in the biracial population of Copiah County, Mississippi. Neurology35:841–845

    Article  PubMed  CAS  Google Scholar 

  • Schoenberg BS, Osuntokun BO, Adeuja AO, et al. (1988): Comparison of the prevalence of Parkinson’s disease in black populations in the rural United States and rural Nigeria: door-to-door community studies. Neurology38:645–646

    Article  PubMed  CAS  Google Scholar 

  • Semchuck KM, Love EJ, Lee RG (1991): Parkinson’s disease and exposure to rural environmental factors: a population based case-control study. Can J Neurol Sci18:279–386

    Google Scholar 

  • Snow B, Wiens M, Hertzman C, Calne DB (1989): A community survey of Parkinson’s disease. Can Med Assoc141:418–422

    CAS  Google Scholar 

  • Spencer PS, Kisby GE, Ludopha AC (1991): Slow toxins, biologic markers, and long-latency neurodegenerative disease in the western Pacific region. Neurology41(Suppl 2):62–66

    Article  PubMed  CAS  Google Scholar 

  • Steventon GB, Heafield MTE, Waring RH, Williams AC (1989): Xenobiotic metabolism in Parkinson’s disease. Neurology39:883–887

    Article  PubMed  CAS  Google Scholar 

  • Tanner CM, Chen B, Wang WZ, et al. (1987): Environmental factors in the etiology of Parkinson’s disease. Can J Neurol Sci14:419

    PubMed  CAS  Google Scholar 

  • Tanner CM, Cohen JC, Summerville BC, Goetz CG (1988): Vitamin use and Parkinson’s disease. Ann Neurol233:182

    Google Scholar 

  • Teräväinen H, Forgach L, Hietanen M, Schulzer M, Schoenberg BS, Calne DB (1986): The age of onset of Parkinson’s disease, etiologic implications. Can J Neurol Sci13:317

    PubMed  Google Scholar 

  • Tetrud JW, Langston JW (1987): L-Deprenyl as a possible protective agent in Parkinson’s disease. J Neural transm25:69–79

    CAS  Google Scholar 

  • Wang Y, Shi Y, Wu S, He Y, Zhang B (1991): Parkinson’s disease in China. Chin Med J33:960–964

    Google Scholar 

  • Waring RH, Sturman SG, Smith MCG, Steventon GB, Heafield MTE, Williams AC (1989): S-Methylation in motor neuron disease and Parkinson’s disease. Lancet2:356–357

    Article  PubMed  CAS  Google Scholar 

  • Wender M, Pruchnik D, Kowal P, Florczak J, Zalejski M (1989): Epidemiology of Parkinson’s disease in the Pozna’n province. Przegl Epidemiol43:150–155

    PubMed  CAS  Google Scholar 

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Koller, W.C. (1994). Neuroepidemiology of Parkinson’s Disease: Environmental Influences. In: Mizuno, Y., Calne, D.B., Horowski, R. (eds) Etiopathogenesis. Advances in Research on Neurodegeneration, vol 2. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4684-9203-3_4

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  • DOI: https://doi.org/10.1007/978-1-4684-9203-3_4

  • Publisher Name: Birkhäuser, Boston, MA

  • Print ISBN: 978-1-4684-9205-7

  • Online ISBN: 978-1-4684-9203-3

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