Tachykinins, Tachykinin Receptors, and the Central Control of the Cardiovascular System

  • Cinda J. Helke
  • Hiroyuki Ichikawa


The term “tachykinin,” which literally means “fast acting,” refers to a family of peptides that contains the C-terminal sequence of -Phe-X-Gly-Leu-Met-NH2. The best known of these agents, the undecapeptide substance P (SP), was first isolated as a component of a crude extract of equine intestine and brain prepared by von Euler and Gaddum (1931).


Nucleus Tractus Solitarius Rostral Ventrolateral Medulla Carotid Sinus Nerve Tachykinin Receptor Sympathetic Preganglionic Neuron 


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© Birkhäuser Boston 1992

Authors and Affiliations

  • Cinda J. Helke
  • Hiroyuki Ichikawa

There are no affiliations available

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