Respiratory-Sympathetic Integration in the Medulla Oblongata

  • Patrice G. Guyenet
  • Naohiro Koshiya


Homeostasis of tissue pO2 and pCO2 requires that pulmonary gas exchanges be matched by an adequate cardiac output and an appropriate distribution of the regional blood flows. This is achieved through the coordination of the various respiratory motor outputs (phrenic, intercostal, abdominal, laryngeal, pharyngeal, and bronchiomotor) with those governing vasomotion (sympathetic and cardiovagal). This chapter reviews some of the mechanisms responsible for the generation of a coordinated respiratory and sympathetic outflow. The related problem of how the cardiovagal parasympathetic output is matched to the respiratory activity will not be examined here (for reviews see Feldman and Ellenberger, 1988; Spyer and Gilbey, 1988; Richter and Spyer, 1990).


Medulla Oblongata Nucleus Tractus Solitarius Sympathetic Outflow Ventrolateral Medulla Rostral Ventrolateral Medulla 
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© Birkhäuser Boston 1992

Authors and Affiliations

  • Patrice G. Guyenet
  • Naohiro Koshiya

There are no affiliations available

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