Lack of Suppressor T Cells in Renal Transplant Recipients and Activation by Aminophylline

  • Batya Shohat
  • Zaki Shapira
  • Henry Joshua
  • Ciro Servadio
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)

Abstract

A striking parallel between the failure to improve recent transplant results and unchanging transplant immunosuppression exists today. The present study was undertaken in order to clarify whether aberrations of suppressor T cells occur in renal transplant recipients and whether activation of this immunoregulatory T cell subset by aminophylline administration could have any beneficial effect in the treatment of acute steroid resistant rejection of the transplanted kidney.

Keywords

Creatinine Prednisone Theophylline Rosen Methylprednisolone 

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Batya Shohat
    • 1
  • Zaki Shapira
    • 1
  • Henry Joshua
    • 1
  • Ciro Servadio
    • 1
  1. 1.Clinical Laboratory and Transplantation Unit, Department of Urology, Beilinson Medical Center, Petah Tikva and the Sackler School of MedicineTel Aviv UniversityIsrael

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