Functional Studies on Subpopulations of B-Lymphocytes and Bone Marrow Cells

  • A. Chayen
  • S. Marshall-Clarke
  • R. M. E. Parkhouse
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)


There has recently been much work directed towards describing functionally distinct classes of lymphocytes and charting their ontogeny from a multipotential stem cell in the bone marrow. The T-cell lineage has been extensively studied using the surface markers available (1,2). Although a number of studies do suggest the existence of subpopulations of B-cells, a system of functional markers analogous to the Lyt system of T-cells has not yet been defined.


Bone Marrow Cell Spleen Cell Multipotential Stem Cell FACS Profile Hybrid Culture 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • A. Chayen
    • 1
  • S. Marshall-Clarke
    • 1
  • R. M. E. Parkhouse
    • 1
  1. 1.Division of ImmunologyNational Institute for Medical ResearchLondonEngland

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