Subpopulations of T Cells in the Rat that Mediate Graft-Versus-Host Reactions and Lethal Graft-Versus-Host Disease
Work on experimental animals has shown that the induction of g-v-h disease in F1 recipients by parental lymphoid cells can be prevented by the removal of T cells from the donor inoculum (1). However, a number of alloaggressive effector mechanisms may be mediated by T cells and it is unclear which of these are important in the pathogenesis of g-v-h disease.
KeywordsPopliteal Lymph Node Immunoperoxidase Technique Graft Versus Host Becton Dickinson FACS Haematoxylin Counterstain
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