Gut and Bronchus Associated Lymphoid Tissue: An Overview

  • John Bienenstock
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 149)


Just over 300 years ago, Peyer (1) described structures present in the wall of the ileum before the ileo-cecal junction. Because, when these were pressed, it appeared that fluid was coming from them. He thought that they were glands which had something to do with the digestive process. It has been known for 100 years or more that Peyer’s patches were in reality a collection of lymphoid aggregates and that these were found, some in constant positions, in the gastrointestinal tract from the jejunum distally, including one or two in the colon. In 1875, Klein (2) described lymphoid tissue within the wall of the bronchus in a number of species including man. On the basis of their morphology, he concluded that they were analogous in function to the Peyer’s patches and tonsils.


Lymphoid Tissue Lamina Propria Mesenteric Node Thoracic Duct Mucosal Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • John Bienenstock
    • 1
  1. 1.Department of Pathology and Host Resistance ProgramMcMaster UniversityHamiltonCanada

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